Title:
【発明の名称】新規ビタミンD類似体
Document Type and Number:
Japanese Patent JP3246914
Kind Code:
B2
Abstract:
Vitamin D derivs. of formula (I) are new. In (I) X = H or OH, R1 and R2 = H, 1-6C hydrocarbyl, or together with C (asterisk) bearing the X gp. can form a 3-8C carbocyclic ring; Q = single bond or 1-8C hydrocarbylene diradical; Hydrocarbylene = residue after removal of 1 or 2H from hydrocarbon; m = 0, 1 or 2. R1, R2 Q opt. substd. with deuterium or F; C(.) atom opt. substd. by deuterium, F or 1-2C alkyl gp. and derivs. of (I) where OH gp. are O-acyl, O-glycosyl gp. f or phosphate ester, or masked gp. hydrolysable in-vivo. Also described 1(S),3(R)-bis-tert-butyldimethyl silyloxy-2O(R)-2,2-dichlorovinyl-9, 10-seco-pregna-5(E),7(E),10(19)-triene as an intermediate.
More Like This:
| WO/2007/110109 | NOVEL METHOD |
| WO/1993/009093 | VITAMIN D AMIDE DERIVATIVES |
| JP2014507375 | Calcium-sensing receptor active compound |
Inventors:
Brettin, Claus Ohe Svensgow
Application Number:
JP51385491A
Publication Date:
January 15, 2002
Filing Date:
July 11, 1991
Export Citation:
Assignee:
LEO PHARMACEUTICAL PRODUCTS LIMITED ACTISELSCAB (LEVENS CHEMISKE FABRIC PRODUCTIONS ACTISELSCAB)
International Classes:
A61K31/59; A61K31/593; A61P3/02; A61P3/08; A61P9/12; A61P17/00; A61P29/00; A61P35/00; A61P37/00; A61P37/04; A61P43/00; C07C401/00; (IPC1-7): C07C401/00
Domestic Patent References:
| JP29860A |
Other References:
【文献】国際公開91/271(WO,A1)
【文献】米国特許4804502(US,A)
【文献】米国特許4804502(US,A)
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)