Title:
【発明の名称】新規ビタミンD類似体
Document Type and Number:
Japanese Patent JP3256223
Kind Code:
B2
Abstract:
PCT No. PCT/DK90/00323 Sec. 371 Date Mar. 17, 1992 Sec. 102(e) Date Mar. 17, 1992 PCT Filed Dec. 10, 1990 PCT Pub. No. WO91/09841 PCT Pub. Date Jul. 11, 1991.The present invention relates to compounds of formula (I) (I) in which R1 and R2 may be the same or different and stand for hydrogen, lower alkyl, lower cycloalkyl, or, taken together with the carbon atom (starred in formula I), bearing the groups X, R1 and R2, can form a C3-C8 carbocyclic ring; X stands for hydrogen or hydroxy, R3 and R4, which may be the same or different stand for hydrogen, lower alkyl or halogen, n is 0, 1 or 2 and m is 0, 1 or 2. The present compounds, which find use both in the human and veterinary practice, show an immunomodulating effect as well as strong activity in inducing differentiation and inhibiting undesirable proliferation of certain cells, including cancer cells and skin cells.
Inventors:
Hansen, Kai
Application Number:
JP50220091A
Publication Date:
February 12, 2002
Filing Date:
December 10, 1990
Export Citation:
Assignee:
Leo Pharmaceutical Products Limited A/S
International Classes:
A61P3/08; A61P3/10; A61P9/12; A61P11/00; A61P11/06; A61P29/00; A61P35/00; A61P37/00; A61K31/59; A61P37/02; C07C401/00; (IPC1-7): C07C401/00; A61K31/59; A61P3/10; A61P9/12; A61P11/06; A61P29/00; A61P35/00; A61P37/02
Domestic Patent References:
| JP61267548A | ||||
| JP61267550A |
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)
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