Title:
【発明の名称】内因性メディエイターの新規誘導体、それらの塩、調製方法、適用及びそれらを含む組成物
Document Type and Number:
Japanese Patent JP2968623
Kind Code:
B2
Abstract:
Derivatives of biologically active molecules containing a primary amine group and a hydroxylated nucleus, and their addition salts with mineral or organic acids, having general formula I: R'R"N-A-B-O-CH2-CO-NH-R(I) A=linear or branched C1-C5 alkylene; B=C4-C10 aromatic nucleus with optional heteroatom, or=group -B1-X-B2-, wherein X=O or C1-C4 alkylene; -NH-R=amine residue or alcohol residue; and R', R"=C1-C5 alkyl, H or hydrophobic radical, and their addition salts with mineral or organic acids, method of preparation, applications, especially to visualization, purification, the preparation of antibodies and the assay of the total hormone, and as drugs, compositions in which they are present and analytical kits.
Inventors:
JATSUKU SHOBOO
MISHERU DERAAJU
ANNU MORERU
RUI SEGU
MISHERU DERAAJU
ANNU MORERU
RUI SEGU
Application Number:
JP20501391A
Publication Date:
October 25, 1999
Filing Date:
May 15, 1991
Export Citation:
Assignee:
IMYUNOTETSUKU SA
International Classes:
A61K38/00; A61K51/00; C07C213/06; C07C217/56; C07C235/04; C07C239/20; C07D209/14; C07D209/16; C07D233/24; C07K1/113; C07K5/06; C07K14/00; C07K16/00; G01N33/50; G01N33/78; (IPC1-7): C07K5/06; A61K51/00; C07D233/24; G01N33/50
Attorney, Agent or Firm:
Takashi Ishida (2 outside)