Title:
【発明の名称】新規な(チア)シクロアルキル〔b〕インドール類、それらの製造法及びそれらを含む医薬組成物
Document Type and Number:
Japanese Patent JP3004566
Kind Code:
B2
Abstract:
(Thia)cycloalkyl(b)indole derivs. of formula (I), their optical isomers and acid or base addn. salts, are new. R1 = Ar-(CH2)n-O-; n = 0, 1-4; Ar = phenyl, naphthyl, thienyl, furyl, pyrrolyl, imidazolyl, pyrazolyl, thiazolyl, isothiazolyl, oxazolyl, isoxazolyl, thiadiazole, oxadiazole, pyridyl, quinolyl, isoquinolyl, indolyl, benzofuryl, or benzothienyl (opt. substd. by one or more halo, alkyl, alkoxy, hydroxy or CF3); R2 = H, halo, alkyl, alkoxy or CF3; R3 = H, alkyl, carboxyalkyl or alkoxycarbonylalkyl; A = -(CH2)m- or a gp. of formula (i); m = 3-6; p = 1-4; alkyl, alkoxy = 1-6C.
Inventors:
Paul Cobert
Brigitte Jamar-Gregor
Catherine Cobert
Dominique manche
Pierre Renard
Gerard Adam
Catherine Nuyen
Brigitte Jamar-Gregor
Catherine Cobert
Dominique manche
Pierre Renard
Gerard Adam
Catherine Nuyen
Application Number:
JP16026995A
Publication Date:
January 31, 2000
Filing Date:
June 27, 1995
Export Citation:
Assignee:
Adair e Company
International Classes:
A61K31/40; A61K31/403; A61K31/41; A61K31/415; A61K31/42; A61K31/425; A61K31/44; A61K31/4427; A61K31/4433; A61K31/47; A61P1/00; A61P9/00; A61P9/10; A61P11/00; A61P11/08; A61P13/02; A61P15/00; A61P17/00; A61P29/00; A61P37/08; A61P43/00; C07D209/94; C07D401/12; C07D409/12; C07D417/12; C07D495/04; (IPC1-7): C07D209/94; A61P29/00; A61P43/00; A61K31/403; A61K31/407; A61K31/433; A61K31/422; A61K31/427; A61K31/4439; A61K31/4709; C07D401/12; C07D409/12; C07D417/12; C07D495/04
Domestic Patent References:
| JP5053386A | ||||
| JP5502222A |
Foreign References:
Other References:
【文献】西独国特許出願公開2243574(DE,A1)
【文献】Chemcal Abstracts,vol.61,要約番号11314
【文献】Chemcal Abstracts,vol.61,要約番号11314
Attorney, Agent or Firm:
Hajime Tsukuni (2 outside)