Title:
【発明の名称】ヌクレオシド誘導体およびその製造方法
Document Type and Number:
Japanese Patent JP3047045
Kind Code:
B2
Abstract:
PCT No. PCT/KR95/00135 Sec. 371 Date Jun. 11, 1997 Sec. 102(e) Date Jun. 11, 1997 PCT Filed Oct. 21, 1995 PCT Pub. No. WO96/12716 PCT Pub. Date May 2, 1996Nucleoside derivatives represented by formula (I); wherein, R1 represents hydrogen, phosphate or phosphonate group, R2 represents substituted or unsubstituted pyrimidine or purine base, and Z represents S, SO, SO2, O or C; or pharmaceutically acceptable salts thereof. Compound (I) can be obtained by reacting a compound of the formula (II); wherein, R7 represents hydrogen or hydroxy-protecting group, L represents aromatic or nonaromatic acyl, halide or alkoxy, and Z represents S, SO, SO2, O or C, with a base.
Inventors:
Kim Jun War
Lee Chung Ryul
Chun Khoon
Unsung Kill
Cha Kyun Hoi
Song Ho Joe
Choi Seung Jo
Jeon Beeon Theon
Minkeeon
Lee Chung Ryul
Chun Khoon
Unsung Kill
Cha Kyun Hoi
Song Ho Joe
Choi Seung Jo
Jeon Beeon Theon
Minkeeon
Application Number:
JP51379196A
Publication Date:
May 29, 2000
Filing Date:
October 21, 1995
Export Citation:
Assignee:
Chun Khun Dan Corporation
International Classes:
A61K31/505; A61K31/52; A61K31/522; A61P1/16; C07D309/06; C07D327/06; C07D405/04; C07D411/04; C07D473/00; C07D473/18; C07D473/34; C07D319/12; C07H19/06; C07H19/16; (IPC1-7): C07D405/04; A61K31/506; A61K31/52; A61P1/16; A61P31/12; C07D309/06; C07D319/12; C07D327/06; C07D411/04; C07D473/18; C07D473/34
Other References:
【文献】米国特許5164488(US,A)
【文献】米国特許5008406(US,A)
【文献】米国特許4827003(US,A)
【文献】米国特許5008406(US,A)
【文献】米国特許4827003(US,A)
Attorney, Agent or Firm:
Eiji Saegusa (2 others)