NEW CULTURE OF EXSEROHILUM ROSTRATUM AND METHOD FOR USING THE SAME

Title:

NEW CULTURE OF EXSEROHILUM ROSTRATUM AND METHOD FOR USING THE SAME

Document Type and Number:

Japanese Patent JPH067150

Kind Code:

A

Abstract:

PURPOSE: To obtain a new microorganism capable of producing a squalene synthetase inhibitor containing no phosphorus and useful as cholesterol suppressants and antimicrobial agents by fermentation.

CONSTITUTION: This invention relates to biologically pure culture of Exserohilum rostratum, capable of producing a compound which inhibits squalene-synthetase activity and is expressed by formula I in an amount to be harvested from a fermentation broth, e.g. a strain MF5565 (ATCC74068). The strain MF5565 is isolated from cacao tree bark harvested in Los-Banos, Laguna, Philippine. The compound of the formula is preferably produced by culturing the above mentioned bacteria in an aerobic condition at pH4.5-7 and 24-26°C.

More Like This:

WO/2022/101404	PROCESS FOR THE PRODUCTION OF A TECHNICAL ENZYME COMPOSITION WITH LOW VISCOSITY PRODUCED BY A FILAMENTOUS FUNGUS
WO/2003/085728	CARRIER, METHOD OF MANUFACTURING A CARRIER AND AN ELECTRONIC DEVICE
JP6940104	Heat-treated gluten, brewed products using it, and methods for producing these

Inventors:

MARIA TERESA DEIESUUMATASU
JIERARUDO EFU BIRUSU
YU RIN KONGU
MEARI NARIN OMUSUTETSUDO
FUERUNANDO PERAESU

Application Number:

JP16960992A

Publication Date:

January 18, 1994

Filing Date:

June 26, 1992

Export Citation:

Click for automatic bibliography generation Help

Assignee:

MERCK & CO INC

International Classes:

C12N1/14; C12N9/00; C12P17/18; C12R1/645; (IPC1-7): C12N1/14; C12P17/18

Attorney, Agent or Firm:

Masao Okabe (5 others)

Next Patent: METHOD FOR PRODUCING POWDERY KOJI AND DEVICE THEREFOR