Title:
【発明の名称】タンパク質分解酵素阻害剤
Document Type and Number:
Japanese Patent JP2701932
Kind Code:
B2
Abstract:
A proteinase inhibitory compound represented by the following general formula (1): wherein R1 represents a straight-chain or branched acyl group having 2 to 10 carbon atoms, a branched-, cyclic- or polycyclic-alkyloxycarbonyl group having 4 to 15 carbon atoms, a substituted- or unsubstituted-benzyloxycarbonyl group, a 2,2,2-trichloroethyloxycarbonyl group, a 2-(trimethylsilyl)ethyloxycarbonyl group, a p-toluenesulfonyl group, an o-nitrophenylsulfenyl group, a diphenylphosphonothioyl group, a triphenylmethyl group or a 2-benzoly-1-methylvinyl group; R2 represents a hydrogen atom; or R1 and R2 may together form a phthaloyl group; R3 represents an isobutyl group, a n-butyl group or an isopropyl group and the above-mentioned R1 can be an unsubstituted-benzyloxycarbonyl group provided that R3 is a n-butyl group; and R4 represents a n-butyl group. e
Inventors:
Naoki Higuchi
Masayuki Saito
Hiroshi Shibata
Masayuki Saito
Hiroshi Shibata
Application Number:
JP8990489A
Publication Date:
January 21, 1998
Filing Date:
April 10, 1989
Export Citation:
Assignee:
Suntory Limited
International Classes:
A61K31/16; A61K31/165; A61K31/695; A61K38/55; A61P17/00; A61P27/02; A61P27/12; A61P29/00; A61P43/00; C07C237/04; C07C237/06; C07C237/22; C12N9/99; C07C271/22; C07C271/34; C07C271/54; C07C311/21; C07C313/24; C07D209/48; C07F7/08; C07F7/10; C07F9/24; C07F9/36; C07F9/44; C07K5/06; A61K38/00; (IPC1-7): C07C237/04; A61K31/16; A61K31/165; A61K31/695; C07C237/22; C07C271/22; C07C271/34; C07C271/54; C07C311/21; C07C313/24; C07F7/10; C07F9/44; C12N9/99
Domestic Patent References:
| JP1121257A |
Attorney, Agent or Firm:
Jun Tsuda (3 others)