Title:
【発明の名称】Ras結合蛋白質(PRE1)
Document Type and Number:
Japanese Patent JP2001518285
Kind Code:
A
Abstract:
Disclosed is a Ras-binding protein designated PRE1. PRE1 occurs naturally in various mammalian tissues and cell types. An isolated DNA encoding PRE1, vectors and cells containing the DNA, and PRE1-specific antibodies are also disclosed. Also disclosed is an in vitro screening method for identifying a substance which modulates PRE1-Ras binding, and an in vitro method for identifying a substance that modulates PRE1 gene expression.
Inventors:
Zhang Kushan-Fen
Avrucci joseph
Avrucci joseph
Application Number:
JP2000513866A
Publication Date:
October 16, 2001
Filing Date:
October 01, 1998
Export Citation:
Assignee:
The General Hospital Corporation
International Classes:
G01N33/50; A61K38/00; A61K45/00; A61P35/00; A61P43/00; C07K14/47; C07K16/18; C07K16/32; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12P21/02; C12P21/08; C12Q1/02; G01N33/15; G01N33/18; G01N33/566; (IPC1-7): C12N15/09; A61K38/00; A61K45/00; A61P35/00; A61P43/00; C07K14/47; C07K16/18; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/02; C12Q1/02; G01N33/15; G01N33/18; G01N33/50; G01N33/566
Attorney, Agent or Firm:
Shimizu Hatsushi (1 person outside)