Title:
【発明の名称】エポキシドまたはグリコール基を有するレニン‐抑制ペプチド
Document Type and Number:
Japanese Patent JPH02501140
Kind Code:
A
Abstract:
Novel renin-inhibitory peptides of the formula X-A6-B7-C8-D9-E10-F11, containing C-terminus truncated epoxy or azido or cyano groups or containing a position 10-11 diol and a position 11-12 retro bond. The present invention further provides novel transition-state analogue inserts which are useful as intermediates for the preparation of renin-inhibitory peptides.
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Inventors:
Tyth Ribbon Gus, Svit
Application Number:
JP50153188A
Publication Date:
April 19, 1990
Filing Date:
November 23, 1987
Export Citation:
Assignee:
The Up John Company
International Classes:
C07D295/18; A61K38/55; A61P5/38; A61P9/00; A61P9/12; C07C59/245; C07C235/06; C07C235/08; C07C237/12; C07C237/22; C07C259/06; C07D233/54; C07D263/04; C07D263/06; C07D295/185; C07D413/04; C07K5/02; C07K5/06; C07K5/065; C07K14/81; A61K38/00; (IPC1-7): C07C237/12; A61K37/64; C07C59/245; C07C235/06; C07C235/08; C07C237/22; C07C259/06; C07D263/04; C07D263/06; C07D295/18; C07D413/04; C07K5/06
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)