【発明の名称】Ihイオンチャンネルの配列およびその使用

Japanese Patent JP2002507394

A

Nucleic acid (I), preferably DNA, encoding an Ih ion-channel, or part of it, and the complements of (I), is new. Independent claims are also included for the following: (1) nucleic acid (Ia) at least 80% homologous with (I); (2) Ih ion-channel polypeptide (II) encoded by (I); (3) method for identifying agents (A) that modulate the activity of ion channels by contacting test compounds with (I) or (II); (4) kits for the process of (3); (5) pharmaceutical composition containing (I) and/or (II); (6) construct containing (I); (7) host cells containing this construct; (8) antibodies (Ab) reactive with (II); and (9) nucleic acid probes specific for (I). ACTIVITY : Analgesic; cardioactive. MECHANISM OF ACTION : The Ih channel participates in the pacemaker function in cardiac muscle.

WO/2012/176853	PROTEIN COMPRISING TRUNCATED FORM OF EXTRACELLULAR DOMAIN PROTEIN OF FRIZZLED 2, AND PHARMACEUTICAL COMPOSITION FOR TREATING BONE DISEASES WHICH COMPRISES SAID PROTEIN
JP2010042009	ANTISENSE IAP NUCLEOBASE OLIGOMER AND USE THEREOF
WO/1998/011229	HISTIDINE-TAGGED SHIGA TOXINS, TOXOIDS, AND PROTEIN FUSIONS WITH SUCH TOXINS AND TOXOIDS, METHODS FOR THE PURIFICATION AND PREPARATION THEREOF

Baumann Arund
Bonique Wolfgang
Gauss Renata
Scholten Alexander
Seifert Reinhard
Kaup Benjamin

JP2000532514A

March 12, 2002

February 12, 1999

Click for automatic bibliography generation  

Forsungszentrum Julich Gamebhaer

A61K31/711; A61K38/00; A61K48/00; A61P9/00; A61P25/00; A61P25/04; A61P25/20; C07K14/435; C07K14/705; C07K16/28; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12N15/12; C12P21/08; C12Q1/68; G01N33/50; G01N33/68; (IPC1-7): C12N15/09; A61K31/711; A61K38/00; A61K48/00; A61P9/00; A61P25/00; A61P25/04; A61P25/20; C07K14/705; C07K16/28; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12Q1/68; G01N33/50; G01N33/68

Nobuto Watanabe (1 person outside)

Previous Patent: 抗原ライブラリー免疫

Next Patent: 開口分泌タンパク質ＥＸＯ１及びＥＸＯ２