Title:
【発明の名称】中性スフィンゴミエリナーゼインヒビターとしての置換アミノ酸
Document Type and Number:
Japanese Patent JP2003521512
Kind Code:
A
Abstract:
This invention relates to a series of substituted amino acids of Formula Ipharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention are small molecules that bind to neutral sphingomyelinase and inhibit its activity.
Inventors:
Wachiter, Michael Pee
Laran, plahul
Laran, plahul
Application Number:
JP2001556252A
Publication Date:
July 15, 2003
Filing Date:
February 01, 2001
Export Citation:
Assignee:
Ortho-McNeill Pharmacy Incorporated
International Classes:
A61K31/19; A61K31/197; A61K31/22; A61K31/405; A61K31/415; A61K31/435; A61K31/4709; A61K38/55; A61P3/10; A61P9/10; A61P19/02; A61P29/00; A61P35/00; A61P43/00; C07C229/14; C07C229/22; C07D209/20; C07D215/12; C07D231/38; C07K5/06; C07K5/072; A61K38/00; (IPC1-7): A61K31/22; A61K31/197; A61K31/405; A61K31/415; A61K31/4709; A61K38/55; A61P3/10; A61P9/10; A61P19/02; A61P29/00; A61P35/00; A61P43/00
Attorney, Agent or Firm:
Heiyoshi Odashima