Title:
【発明の名称】置換キナゾリン誘導体
Document Type and Number:
Japanese Patent JP2002521476
Kind Code:
A
Abstract:
This invention provides a process for preparing compounds of formula (1) wherein: X is phenyl optionally substituted with one or more substituents selected from the group consisting of halogen, alkyl of 1-6 carbon atoms, alkoxy of 1-6 carbon atoms, hydroxy, trifluoromethyl, cyano, nitro, carboxy, carboalkoxy of 2-7 carbon atoms, carboalkyl of 2-7 carbon atoms, amino, and alkanoylamino of 1-6 carbon atoms; R and R<1> are each, independently, hydrogen, halogen, alkyl of 1-6 carbon atoms, alkoxy of 1-6 carbon atoms, hydroxy, or trifluoromethyl; R<2> is hydrogen, alkyl of 1-6 carbon atoms, alkoxy of 1-6 carbon atoms, hydroxy, trifluoromethyl; Y is (2) or (3); R<3> is independently hydrogen, alkyl of 1-6 carbon atoms, carboxy, carboalkoxy of 1-6 carbon atoms, phenyl, or carboalkyl of 2-7 carbon atoms; n = 2-4; or a pharmaceutically acceptable salt thereof, with the proviso that each R<3> of Y may be the same or different.
Inventors:
Gretzos, Constantine
Application Number:
JP2000562358A
Publication Date:
July 16, 2002
Filing Date:
July 28, 1999
Export Citation:
Assignee:
American Home Products Corporation
International Classes:
A61K31/517; A61P35/00; A61P43/00; C07C255/60; C07C257/12; C07C319/20; C07C321/14; C07C323/60; C07D239/94; (IPC1-7): C07D239/94; A61K31/517; A61P35/00; A61P43/00; C07C257/12; C07C319/20; C07C321/14
Attorney, Agent or Firm:
Heiyoshi Odashima