Title:
【発明の名称】置換6‐アザアンドロステノン類
Document Type and Number:
Japanese Patent JPH08504825
Kind Code:
A
Abstract:
The present invention relates to certain substituted 17 beta -substituted carbonyl-6-azaandrost-4-en-3-ones of formula (I), wherein R<1> and R<2> i) are independently hydrogen or lower alkyl and the bond between the carbons bearing R<1> and R<2> is a single or a double bond, or ii) taken together are a -CH2- group forming a cyclopropane ring, and the bond between the carbons bearing R<1> and R<2> is a single bond; R<3> is preferably hydrogen, halogen or lower alkyl, R<4> is preferably hydrogen or lower alkyl, X is preferably CH2, Y is preferably hydrogen and Z is preferably CONR<14>R<15> and R<14> and R<15> are a variety of organic groups, and pharmaceutically acceptable salts thereof, preparation, medical use and pharmaceutical formulations.
Inventors:
Andrews, Robert Curl
Cribs, Cynthia Marquardt
Fly, Stephen Vernon
Haffner, Kurtdale
Maloney, Patrick Reed
Cribs, Cynthia Marquardt
Fly, Stephen Vernon
Haffner, Kurtdale
Maloney, Patrick Reed
Application Number:
JP51537593A
Publication Date:
May 28, 1996
Filing Date:
December 17, 1993
Export Citation:
Assignee:
Glaxo, Welcome, Incorporated
International Classes:
A61P37/08; A61K31/58; C07C211/41; C07C211/45; C07D309/14; C07D317/58; C07D335/02; C07J3/00; C07J73/00; A61K; C07C; C07J; C07J63/00; C07J75/00; (IPC1-7): C07J3/00; A61K31/58
Attorney, Agent or Firm:
Kazuo Sato (2 outside)