Title:
【発明の名称】脈管形成を抑制するためのスラミン・タイプの化合物および脈管形成抑止ステロイド類
Document Type and Number:
Japanese Patent JPH04506066
Kind Code:
A
Abstract:
The invention is a method of treating angiogenesis in a warm blooded mammal who is in need of such treatment which comprises administration of an angiogenic inhibiting amount of a combination of a suramin-type compound and an angiostatic steroid. Angiostatic steroids include the known 20-substituted steroids of formula (I), 21-hydroxy steroids of formula (II), C11-functionalized steroids of formula (III) as well as the novel DELTA <9(11)>-etianic esters of formula (IV), as well as various individual known steroids.
Inventors:
Aristof, Paul A.
Mitchell, Mark A
Wilkes, John W
Mitchell, Mark A
Wilkes, John W
Application Number:
JP50761990A
Publication Date:
October 22, 1992
Filing Date:
May 17, 1990
Export Citation:
Assignee:
The Up John Company
International Classes:
A61K31/185; A61K31/495; A61K31/565; A61K31/57; A61K31/66; A61P3/02; A61P3/08; A61P9/10; A61P9/14; A61P13/02; A61P15/00; A61P17/00; A61P27/02; A61P33/00; A61P35/00; C07J3/00; C07J31/00; C07J43/00; (IPC1-7): A61K31/185; A61K31/495; A61K31/57; A61K31/66; C07J3/00; C07J31/00; C07J43/00
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)