Title:
【発明の名称】パルボウイルスベクターによる標的化した遺伝子改変
Document Type and Number:
Japanese Patent JP2001522244
Kind Code:
A
Abstract:
This invention provides methods for obtaining targeted gene modification in vertebrate cells using parvoviral vectors, including adeno-associated virus (AAV). The parvoviral vectors used in the methods of the invention are capable of targeting a specific genetic modification to a preselected target locus in a cellular genome by homologous pairing.
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Inventors:
Russell, David W.
Hirata, Lori Kay.
Hirata, Lori Kay.
Application Number:
JP54625098A
Publication Date:
November 13, 2001
Filing Date:
April 20, 1998
Export Citation:
Assignee:
University of Washington
International Classes:
A01K67/027; C12N5/10; C12N15/09; C12N15/864; (IPC1-7): C12N15/09; A01K67/027; C12N5/10
Attorney, Agent or Firm:
Shusaku Yamamoto