Title:
【発明の名称】腫瘍ワクチン及びその製造方法
Document Type and Number:
Japanese Patent JP2000502052
Kind Code:
A
Abstract:
Tumor vaccine and process for the preparation thereof. The tumor vaccine contains tumor cells at least some of which contain at least one MHC-I-haplotype of the patient on the cell surface, and which are charged with one or more peptides binding to the MHC-I molecule in such a way that the tumor cells are recognized as foreign by the patient's immune system in context with the peptides and trigger a cellular immune response. The charging is carried out in the presence of a polycation such as polylysine.
Inventors:
Schmid Walter
Billund Steal Max
Schweig Hoffer Tamas
Steinline Peter
Boucheret Michael
Billund Steal Max
Schweig Hoffer Tamas
Steinline Peter
Boucheret Michael
Application Number:
JP51939597A
Publication Date:
February 22, 2000
Filing Date:
November 21, 1996
Export Citation:
Assignee:
Boehringer Ingelheim International Gesellschaft Mitt Beschlenktel Haftung
International Classes:
A61K31/00; A61K35/12; A61K38/00; A61K38/19; A61K38/21; A61K39/00; A61K39/02; A61K39/12; A61K39/145; A61K39/39; A61K48/00; A61P35/00; C07K7/06; C07K14/725; C12N5/10; C07K14/74; C12N5/071; C12N5/09; (IPC1-7): A61K39/00; A61P35/00; A61K35/12; A61K35/14; A61K35/26; A61K38/00; A61K38/21; A61K39/02; A61K39/145; A61K48/00; C07K7/06; C12N5/06; C12N5/10
Attorney, Agent or Firm:
Minoru Nakamura (6 outside)