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Title:
【発明の名称】尿素系リポキシゲナーゼ阻害化合物
Document Type and Number:
Japanese Patent JPH04504261
Kind Code:
A
Abstract:
Substituted phenyl, naphthyl, and thienyl N-hydroxy urea compounds form a class of potent inhibitors of 5- and 12-lipoxygenase and are thus useful compounds in the treatment of inflammatory disease states where leukotrienes and other products of lipoxygenase enzyme activity are implicated.

Inventors:
Burutxu, de doubling
Stilyu Art, Andrey O
Summers, The Ames Bee
Kirkman, Daniel Jei
Martin, Ji
Application Number:
JP50610190A
Publication Date:
July 30, 1992
Filing Date:
March 20, 1990
Export Citation:
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Assignee:
Abbot Laboratories
International Classes:
C12N9/99; A61K31/17; A61K31/195; A61K31/22; A61K31/275; A61K31/38; A61K31/381; A61P29/00; A61P37/00; A61P37/08; A61P43/00; C07C275/64; C07C323/44; C07C323/47; C07C335/40; C07D333/20; C07D333/22; C07D333/28; C07D333/32; C07D333/36; C07D335/08; C07D409/04; C07D409/06; C07D409/12; (IPC1-7): A61K31/17; A61K31/195; A61K31/22; A61K31/275; A61K31/38; C07C275/64; C07C323/44; C07C323/47; C07C335/40; C07D333/20; C07D333/22; C07D333/28; C07D333/32; C07D333/36; C07D409/12; C12N9/99
Attorney, Agent or Firm:
Yoshio Kawaguchi (4 outside)



 
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