Title:
【発明の名称】治療のための使用
Document Type and Number:
Japanese Patent JP2003513035
Kind Code:
A
Abstract:
A method of chemoprevention of the onset of invasive breast cancer in a high risk patient comprises administering to the patient an effective amount of an EGFR tyrosine kinase inhibitor.
Inventors:
Nigel James Band Red
Application Number:
JP2001534360A
Publication Date:
April 08, 2003
Filing Date:
November 01, 2000
Export Citation:
Assignee:
The University of Manchester
International Classes:
A61K45/00; A61K31/00; A61K31/517; A61K31/519; A61K31/5355; A61P35/00; A61P43/00; (IPC1-7): A61K45/00; A61K31/517; A61K31/519; A61K31/5355; A61P35/00; A61P43/00
Domestic Patent References:
| JPH11504033A | 1999-04-06 | |||
| JPH10506633A | 1998-06-30 | |||
| JPH11508570A | 1999-07-27 | |||
| JPH11504031A | 1999-04-06 | |||
| JPH10508875A | 1998-09-02 | |||
| JPH10508024A | 1998-08-04 |
Other References:
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JPN6010048074, ＷＯＯＤＢＵＲＮ，Ｊ．Ｒ．, "Ｔｈｅ ｅｐｉｄｅｒｍａｌ ｇｒｏｗｔｈ ｆａｃｔｏｒ ｒｅｃｅｐｔｏｒ ａｎｄ ｉｔｓ ｉｎｈｉｂｉｔｉｏｎ ｉｎ ｃａｎｃｅｒ ｔｈｅｒａｐｙ", Ｐｈａｒｍａｃｏｌｏｇｙ ＆ ｔｈｅｒａｐｅｕｔｉｃｓ, 199906, Ｖｏｌ．８２， Ｎｏ．２−３, ｐ．２４１−５０
JPN5002017549, ＭＣＫＩＮＮＯＮ Ｃ, ＩＤＲＵＧＳ, 199907, Ｖ２ Ｎ７, Ｐ６３３−６３５
JPN5002017550, ＢＲＩＤＧＥＳ Ａ．Ｊ．, ＥＭＥＲＧＩＮＧ ＤＲＵＧＳ, 1998, Ｖ３, Ｐ２７９−２９２
JPN5002017543, ＤＲＩＳＣＯＬＬ Ｄ, ＰＲＯＣＥＥＤＩＮＧＳ ＯＦ ＴＨＥ ＡＭＥＲＩＣＡＮ ＡＳＳＯＣＩＡＴＩＯＮ ＦＯＲ ＣＡＮＣＥＲ ＲＥＳＥＡＲＣＨ ＡＮＮＵＡＬ, 199903, Ｖ４０, Ｐ１２１, US
JPN6010048077, ＲＯＳＦＪＯＲＤ，Ｅ．Ｃ． ｅｔ ａｌ, "Ｇｒｏｗｔｈ ｆａｃｔｏｒｓ， ａｐｏｐｔｏｓｉｓ， ａｎｄ ｓｕｒｖｉｖａｌ ｏｆ ｍａｍｍａｒｙ ｅｐｉｔｈｅｌｉａｌ ｃｅｌｌｓ", Ｊｏｕｒｎａｌ ｏｆ ｍａｍｍａｒｙ ｇｌａｎｄ ｂｉｏｌｏｇｙ ａｎｄ ｎｅｏｐｌａｓｉａ, 199904, Ｖｏｌ．４， Ｎｏ．２, ｐ．２２９−３７
JPN6010048083, ＡＮＫＲＡＰＰ，Ｄ．Ｐ． ｅｔ ａｌ, "Ｒｏｌｅ ｏｆ ｅｐｉｄｅｒｍａｌ ｇｒｏｗｔｈ ｆａｃｔｏｒ ｉｎ ｔｈｅ ａｃｑｕｉｓｉｔｉｏｎ ｏｆ ｏｖａｒｉａｎ ｓｔｅｒｏｉｄ ｈｏｒｍｏｎｅ ｒｅｓｐｏｎｓｉｖｅｎｅｓｓ ｉｎ ｔｈｅ", Ｊｏｕｒｎａｌ ｏｆ ｃｅｌｌｕｌａｒ ｐｈｙｓｉｏｌｏｇｙ, 1998, Ｖｏｌ．１７４， Ｎｏ．２, ｐ．２５１−６０
JPN6010048074, ＷＯＯＤＢＵＲＮ，Ｊ．Ｒ．, "Ｔｈｅ ｅｐｉｄｅｒｍａｌ ｇｒｏｗｔｈ ｆａｃｔｏｒ ｒｅｃｅｐｔｏｒ ａｎｄ ｉｔｓ ｉｎｈｉｂｉｔｉｏｎ ｉｎ ｃａｎｃｅｒ ｔｈｅｒａｐｙ", Ｐｈａｒｍａｃｏｌｏｇｙ ＆ ｔｈｅｒａｐｅｕｔｉｃｓ, 199906, Ｖｏｌ．８２， Ｎｏ．２−３, ｐ．２４１−５０
JPN5002017549, ＭＣＫＩＮＮＯＮ Ｃ, ＩＤＲＵＧＳ, 199907, Ｖ２ Ｎ７, Ｐ６３３−６３５
JPN5002017550, ＢＲＩＤＧＥＳ Ａ．Ｊ．, ＥＭＥＲＧＩＮＧ ＤＲＵＧＳ, 1998, Ｖ３, Ｐ２７９−２９２
JPN5002017543, ＤＲＩＳＣＯＬＬ Ｄ, ＰＲＯＣＥＥＤＩＮＧＳ ＯＦ ＴＨＥ ＡＭＥＲＩＣＡＮ ＡＳＳＯＣＩＡＴＩＯＮ ＦＯＲ ＣＡＮＣＥＲ ＲＥＳＥＡＲＣＨ ＡＮＮＵＡＬ, 199903, Ｖ４０, Ｐ１２１, US
JPN6010048077, ＲＯＳＦＪＯＲＤ，Ｅ．Ｃ． ｅｔ ａｌ, "Ｇｒｏｗｔｈ ｆａｃｔｏｒｓ， ａｐｏｐｔｏｓｉｓ， ａｎｄ ｓｕｒｖｉｖａｌ ｏｆ ｍａｍｍａｒｙ ｅｐｉｔｈｅｌｉａｌ ｃｅｌｌｓ", Ｊｏｕｒｎａｌ ｏｆ ｍａｍｍａｒｙ ｇｌａｎｄ ｂｉｏｌｏｇｙ ａｎｄ ｎｅｏｐｌａｓｉａ, 199904, Ｖｏｌ．４， Ｎｏ．２, ｐ．２２９−３７
JPN6010048083, ＡＮＫＲＡＰＰ，Ｄ．Ｐ． ｅｔ ａｌ, "Ｒｏｌｅ ｏｆ ｅｐｉｄｅｒｍａｌ ｇｒｏｗｔｈ ｆａｃｔｏｒ ｉｎ ｔｈｅ ａｃｑｕｉｓｉｔｉｏｎ ｏｆ ｏｖａｒｉａｎ ｓｔｅｒｏｉｄ ｈｏｒｍｏｎｅ ｒｅｓｐｏｎｓｉｖｅｎｅｓｓ ｉｎ ｔｈｅ", Ｊｏｕｒｎａｌ ｏｆ ｃｅｌｌｕｌａｒ ｐｈｙｓｉｏｌｏｇｙ, 1998, Ｖｏｌ．１７４， Ｎｏ．２, ｐ．２５１−６０
Attorney, Agent or Firm:
Toshio Yano (3 outside)