PURPOSE: To obtain a phenoxyalkylaminedicarboxylic acid imide which is useful as an insecticide, acaricide, microbicide and the like by reaction of an amide with a pyrazolecarboxylic halide in the presence of an organic base.
CONSTITUTION: The reaction of a compound of formula I [R1 is an alkyl; R2 is an alkyl, -A-O-R7 (A is a 1-4C alkylene chain; R7 is an alkyl); R3 is H, an alkyl; R4 is an alkyl] with a compound of formula II (R5 is H, an alkyl, a cycloalkyl; R6 is H, halogen; X is halogen) is carried out in the presence of an organic base (for example, triethylamine) in a solvent such as ethyl acetate at 50-180°C to give a compound of formula III. The compound of formula II is used in an amount of 1-2-fold moles; the base is in 1-2-fold moles and the solvent is in a 1-50-fold amount based on the compound of formula I. The use of an organic base rather than an inorganic base markedly increases the yield of the compound of formula III.
OMORI KIYOSHI
FUSE KENSAKU
