Title:
【発明の名称】放出制御されたブプロピオン製剤
Document Type and Number:
Japanese Patent JP2002537319
Kind Code:
A
Abstract:
A controlled release dosage form of bupropion hydrochloride which comprises:(a) a first pellet having a core of bupropion hydrochloride and hydroxypropyl methylcellulose at a weight ratio of 10:1 to 30:1 and a coating of a mixture of an acrylic resin which is soluble in acidic media and ethyl cellulose;(b) a second pellet having a core of bupropion hydrochloride and hydroxypropyl methylcellulose at a ratio of 10:1 to 30:1; an inner coating of a mixture of an acrylic resin which is soluble in acidic media and a water insoluble polymer and an outer coating which comprises an enteric coating polymer.
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Inventors:
Chen, Chi-ming
Jae, Chumbo
Jean, Steve
Jae, Chumbo
Jean, Steve
Application Number:
JP2000600622A
Publication Date:
November 05, 2002
Filing Date:
February 24, 2000
Export Citation:
Assignee:
Andlux Pharmaceuticals, Inc.
International Classes:
A61K9/20; A61K9/52; A61K9/54; A61K9/58; A61K9/50; (IPC1-7): A61K31/135; A61K9/58; A61K9/62; A61K47/14; A61K47/26; A61K47/32; A61K47/38; A61P25/24
Domestic Patent References:
| JPH08500110A | 1996-01-09 | |||
| JPS59155312A | 1984-09-04 | |||
| JPH0256418A | 1990-02-26 | |||
| JPH09500866A | 1997-01-28 | |||
| JPH04501411A | 1992-03-12 | |||
| JPH01230513A | 1989-09-14 | |||
| JPS62258316A | 1987-11-10 |
Other References:
新・薬剤学総論, vol. 改訂第３版, JPN6010027404, 1987, pages 262 - 7, ISSN: 0001621028
Attorney, Agent or Firm:
Toru Sakamoto (1 person outside)