Title:
【発明の名称】ノイラミニダーゼのための化学発光性基質、ノイラミニダーゼの検出のための検定およびそのためのキット
Document Type and Number:
Japanese Patent JP2002530288
Kind Code:
A
Abstract:
The present invention discloses chemiluminescent 1,2-dioxetane substrates capable of reacting with a neuraminidase to release optically detectable energy. These 1,2-dioxetanes have the general formula:wherein Z isand the variables are selected so as to induce decomposition of said dioxetane accompanied by chemiluminescence where Z is cleaved by neuraminidase present.
Inventors:
Bronstein, Irena
Edwards, brooks
Joo, Lou-Long
Edwards, brooks
Joo, Lou-Long
Application Number:
JP2000582406A
Publication Date:
September 17, 2002
Filing Date:
November 17, 1999
Export Citation:
Assignee:
TROPIX,INC.
International Classes:
G01N21/78; C07H7/00; C07H15/203; C07H15/26; C12Q1/34; (IPC1-7): C07H15/26; G01N21/78
Domestic Patent References:
| JPH08134061A | 1996-05-28 | |||
| JPH1090186A | 1998-04-10 | |||
| JPH05287267A | 1993-11-02 | |||
| JPH07509736A | 1995-10-26 | |||
| JPH05505099A | 1993-08-05 |
Foreign References:
| WO1999031280A1 | 1999-06-24 | |||
| WO1998019989A1 | 1998-05-14 |
Attorney, Agent or Firm:
Hajime Tsukuni (1 person outside)