【発明の名称】薬学的活性化合物の制御された送達のための共役付加反応

Title:

【発明の名称】薬学的活性化合物の制御された送達のための共役付加反応

Document Type and Number:

Japanese Patent JP2003535066

Kind Code:

A

Abstract:

The invention features polymeric biomaterials formed by nucleophilic addition reactions to conjugated unsaturated groups. These biomaterials may be used for medical treatments.

Inventors:

Hubbell Jeffrey A.
Erbert Donald
Shoenmakers Ronald

Application Number:

JP2002500775A

Publication Date:

November 25, 2003

Filing Date:

June 04, 2001

Export Citation:

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Assignee:

Aid Genosik Technisk Hokuschule Zurich
UNIVERSITAET ZUERICH

International Classes:

C12N15/09; A61K31/337; A61K31/4745; A61K31/513; A61K31/565; A61K38/00; A61K45/00; A61K47/32; A61K47/34; A61K47/36; A61K47/40; A61K47/48; A61L27/54; A61P31/00; A61P35/00; C07K7/06; C07K7/08; C07K14/48; C07K19/00; (IPC1-7): A61K47/48; A61K31/337; A61K31/4745; A61K31/513; A61K31/565; A61K38/00; A61K45/00; A61K47/32; A61K47/34; A61K47/36; A61K47/40; A61P31/00; A61P35/00

Domestic Patent References:

JPH11513985A	1999-11-30
JP2002535108A	2002-10-22
JP2003503464A	2003-01-28

Foreign References:

WO1998056425A1	1998-12-17
WO2000024782A2	2000-05-04

Other References:

JPN6011055391; ＧＲＥＥＮＷＡＬＤ，Ｒ．Ｂ．　ｅｔ　ａｌ: 'Ｃａｍｐｔｏｔｈｅｃｉｎ-２０-ＰＥＧ　ｅｓｔｅｒ　ｔｒａｎｓｐｏｒｔ　ｆｏｒｍｓ：　ｔｈｅ　ｅｆｆｅｃｔ　ｏｆ　ｓｐａｃｅｒ　ｇｒｏｕｐｓ　ｏｎ　ａｎｔｉｔｕｍｏｒ　ａｃｔｉｖｉｔｙ' Ｂｉｏｏｒｇ　Ｍｅｄ　ＣｈｅｍＶｏｌ．６，　Ｎｏ．５, 1998, ｐ．５５１-５６２
JPN6011055394; ＰＥＮＤＲＩ，Ａ．　ｅｔ　ａｌ: 'Ａｎｔｉｔｕｍｏｒ　ａｃｔｉｖｉｔｙ　ｏｆ　ｐａｃｌｉｔａｘｅｌ-２'-ｇｌｙｃｉｎａｔｅ　ｃｏｎｊｕｇａｔｅｄ　ｔｏ　ｐｏｌｙ（ｅｔｈｙｌｅｎｅ　ｇｌｙｃｏｌ）：　ａ　ｗａｔｅｒ-ｓｏｌｕｂｌｅ　ｐ' Ａｎｔｉｃａｎｃｅｒ　Ｄｒｕｇ　ＤｅｓＶｏｌ．１３，　Ｎｏ．５, 1998, ｐ．３８７-３９５
JPN6011055396; ＫＯＰＥＣＥＫ，Ｊ．　ｅｔ　ａｌ: 'Ｃｏｎｔｒｏｌｌｅｄ　ｒｅｌｅａｓｅ　ｏｆ　ｄｒｕｇ　ｍｏｄｅｌ　ｆｒｏｍ　Ｎ-（２-ｈｙｄｒｏｘｙｐｒｏｐｙｌ）-ｍｅｔｈａｃｒｙｌａｍｉｄｅ　ｃｏｐｏｌｙｍｅｒｓ' Ａｎｎ　Ｎ　Ｙ　Ａｃａｄ　ＳｃｉＶｏｌ．４４６, 1985, ｐ．９３-１０４

Attorney, Agent or Firm:

Shimizu Hatsushi (1 person outside)

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