【発明の名称】エンドセリン拮抗活性を有する複素芳香環縮合シクロペンテン誘導体

Title:

【発明の名称】エンドセリン拮抗活性を有する複素芳香環縮合シクロペンテン誘導体

Document Type and Number:

Japanese Patent JP2847969

Kind Code:

B2

Abstract:

A cyclopentene derivative represented by general formula (I) and a pharmaceutically acceptable salt thereof: wherein Ar<1> and Ar<2> represent each independently phenyl, thienyl, pyridyl, indolyl, benzofuranyl or dihydrobenzofuranyl; A represents a group that is combined with the adjacent carbon-carbon double bond to form a 5-or 6-membered heteroaromatic ring containing one to four heteroatoms selected from the group consisting of nitrogen, oxygen and sulfur; and Y represents -CO-R<4>, SO3H, PO3H2, tetrazol-5-yl, 2-oxo-3H-1,2,3,5-oxathiadiazol-4-yl or 5-oxo-4H-1,2,4-oxadiazol-3-yl.

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Inventors:

ISHIKAWA KYOBUMI
NAGASE TOSHIO
MASE TOSHIAKI
HAYAMA TAKASHI
IHARA MASAKI
NISHIKIBE MASARU
YANO MITSUO

Application Number:

JP50686595A

Publication Date:

January 20, 1999

Filing Date:

August 16, 1994

Export Citation:

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Assignee:

BANJU SEIYAKU KK

International Classes:

A61K31/00; A61K31/44; C07D221/04; C07D401/04; C07D405/04; C07D405/14; C07D409/14; C07D413/14; C07D417/14; C07D419/04; (IPC1-7): C07D221/04; A61K31/00; C07D401/04; C07D405/04; C07D405/14; C07D409/14; C07D413/14

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