Title:
【発明の名称】利尿または降圧作用を有する医薬組成物
Document Type and Number:
Japanese Patent JPS6058725
Kind Code:
B2
Abstract:
Compsn. with diuretic and hypotensive activities comprises per unit dose, about 100-500mg of 4-(2-thenoyl)-2,3-di-chlorophenoxyacetic acid (I) or one its alkali metal salts, or base addn. salts and about 25-100mg. of triamterene (II) plus a pharmaceutically acceptable vehicle. Pref. the wt. ratio (I):(II) is 10:1, esp. 250mg (I) and 25 mg.(II). Compsn. esp. for use in cases of oedema associated with hyperlipidaemia. There is a synergistic association between (I) and (II) which increases the excretion of Na ions but reduces that of K ions.
Inventors:
NIKORASU UIRIAMU JICHURIO
CHAARUZU PATORITSUKU ROMAN
ARUFURETSUDO ROORANDO MAASU
HARII RINKU SAUNDAAZU
CHAARUZU PATORITSUKU ROMAN
ARUFURETSUDO ROORANDO MAASU
HARII RINKU SAUNDAAZU
Application Number:
JP1664177A
Publication Date:
December 21, 1985
Filing Date:
February 17, 1977
Export Citation:
Assignee:
SMITHKLINE BECKMAN CORP
International Classes:
C07D333/22; A61K31/38; A61K31/381; A61K31/40; A61K31/475; A61K31/505; A61K31/519; A61K31/785; A61P7/10; A61P9/12; C07D475/08; (IPC1-7): A61K31/505; A61K31/505
Attorney, Agent or Firm:
Aoyama
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