Title:
【発明の名称】ジアゾメタンの大規模バッチ製造方法
Document Type and Number:
Japanese Patent JP3017982
Kind Code:
B2
Abstract:
Production of diazomethane comprises: (a) adding a solution of at least about 50 g-moles of an N-methyl-N-nitroso amine of formula (I) in an organic solvent that: (i) forms a separate phase when contacted with water; and (ii) has a boiling point less than about 40[deg]C to a reaction vessel containing an aqueous solution of an excess of inorganic base relative to (I) and a phase-transfer catalyst while maintaining the contents of the reaction vessel at a temperature high enough to vaporise both the organic solvent and diazomethane thus formed, the rate of addition of (I) and the temperature of the reaction vessel maintained such that the diazomethane concentration in the liquid phase in the reaction vessel is maintained at 3 weight % or less and the diazomethane concentration in the vapour phase produced is maintained at about 25 mole % or less; and (b) condensing the vapour phase formed to give an organic liquid solution of diazomethane. R = electron-withdrawing group.
Inventors:
Thomas G. Archbold
Dersin Huang
Mark H. Plato
James C. Bernard
Dersin Huang
Mark H. Plato
James C. Bernard
Application Number:
JP32241698A
Publication Date:
March 13, 2000
Filing Date:
November 12, 1998
Export Citation:
Assignee:
Aero Jet Fine Chemicals LLC
International Classes:
C07B61/00; C07C245/16; B01J31/02; (IPC1-7): C07C245/16; B01J31/02
Domestic Patent References:
| JP6351366A | ||||
| JP11209330A |
Other References:
【文献】米国特許5459243(US,A)
Attorney, Agent or Firm:
Shoichi Hase