Title:
【発明の名称】ヒト抗トロンビン3の変異体
Document Type and Number:
Japanese Patent JP3226215
Kind Code:
B2
Abstract:
Mutants of AT III which are advantageously modified at one or more potential glycosylation sites or at position Arg393 are described. The combination of the mutations usually potentiates the advantageous modifications.
Inventors:
Gert, Zettlmaisl
Hermann, Erich, Calges
Achim, Becker
Hermann, Erich, Calges
Achim, Becker
Application Number:
JP1471290A
Publication Date:
November 05, 2001
Filing Date:
January 24, 1990
Export Citation:
Assignee:
AVENTIS BEHRING GMBH
International Classes:
C12N9/99; A61K38/00; A61K38/55; A61P7/02; C07H21/04; C07K14/81; C12N1/21; C12N15/09; C12N15/15; C12P21/02; C12R1/19; (IPC1-7): C07K14/81; A61K38/00; A61K38/55; A61P7/02; C12N9/99; C12P21/02
Other References:
Ｂｌｏｏｄ，Ｖｏｌ．７２，Ｎｏ．５，Ｐ．１８１７−１８２１（１９８８）
Ｊ．Ｂｉｏｌ．Ｃｈｅｍ．，Ｖｏｌ．２６３，Ｎｏ．３１，Ｐ．１５８４９−１５８５２（１９８８）
Ｊ．Ｂｉｏｌ．Ｃｈｅｍ．，Ｖｏｌ．２６３，Ｎｏ．３１，Ｐ．１５８４９−１５８５２（１９８８）
Attorney, Agent or Firm:
Kazuo Sato (2 outside)