【発明の名称】潰瘍抑制化合物類の製造に有用な新規中間体

Title:

【発明の名称】潰瘍抑制化合物類の製造に有用な新規中間体

Document Type and Number:

Japanese Patent JPS595581

Kind Code:

B2

Abstract:

Anti-ulcer agents of the formula I wherein R1 is a straight or branched chain alkynyl group containing from 3 to 9 carbon atoms, inclusive, are prepared by reacting a compound of the formula II wherein X is a conventional leaving group, preferably in the form of its acid addition salt, with a compound of the formula III wherein R1 is as defined above. The intermediates of Formula III may be prepared by reacting a cysteamine salt with an isothiourea of the formula V wherein R1 is as described above, in the presence of a base.

Inventors:

RONNII REI KURENSHO
JOOJI MITSUCHERU RAAKU

Application Number:

JP3483080A

Publication Date:

February 06, 1984

Filing Date:

March 21, 1980

Export Citation:

Click for automatic bibliography generation Help

Assignee:

BRISTOL MYERS CO

International Classes:

C07C335/38; A61K31/415; A61P1/00; A61P1/04; C07C67/00; C07C313/00; C07C323/44; C07C325/00; C07D233/54; C07D233/64; C07D277/64; (IPC1-7): C07C157/14

Attorney, Agent or Firm:

Ryoji Kawase

Next Patent: BIDIRECTIONAL SIGNAL TRANSMITTING SYSTEM