Title:
【発明の名称】改善された作用効果を有する新規LH―RH―拮抗剤
Document Type and Number:
Japanese Patent JP2000501083
Kind Code:
A
Abstract:
New LH-RH antagonists are disclosed, in particular peptidomimetics and peptides modified in a side chain, their salts with pharmaceutically acceptable acids and a process for preparing these LH-RH antagonists and their salts. The disclosed peptides represent analogues of the luteinising hormone releasing hormone (LH-RH). The disclosed compounds have a high antagonistic power and are free of undesirable side effects, in particular edematogenic effects.
Inventors:
Bernhard Kutcher
Michael Bernd
Thomas beckers
Thomas Clener
Peter-Paul Emihi
Patricia-Marie Charpentier
Michael Bernd
Thomas beckers
Thomas Clener
Peter-Paul Emihi
Patricia-Marie Charpentier
Application Number:
JP52005497A
Publication Date:
February 02, 2000
Filing Date:
November 14, 1996
Export Citation:
Assignee:
Asta Medica Actien Gezel Shaft
International Classes:
A61K31/00; A61K31/165; A61K31/166; A61K31/215; A61K31/216; A61K31/275; A61K31/34; A61K31/341; A61K31/40; A61K31/401; A61K31/4015; A61K31/403; A61K31/404; A61K31/415; A61K31/416; A61K31/4164; A61K31/4184; A61K31/44; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/4427; A61K31/4439; A61K31/445; A61K31/454; A61K31/47; A61K31/535; A61K31/5355; A61K31/5375; A61K38/04; A61K38/08; A61P5/00; A61P35/00; C07C257/18; C07C271/22; C07D249/08; C07D207/27; C07D209/08; C07D211/14; C07D213/40; C07D213/61; C07D213/64; C07D213/75; C07D213/80; C07D213/84; C07D215/14; C07D215/22; C07D231/56; C07D233/26; C07D233/32; C07D233/61; C07D233/64; C07D235/14; C07D235/16; C07D239/42; C07D257/04; C07D295/12; C07D307/52; C07D471/04; C07D487/04; C07D521/00; C07K5/00; C07K5/06; C07K7/06; C07K7/23; A61K38/00; C07D207/26; (IPC1-7): C07C257/18; A61P5/00; A61K31/166; A61K31/216; A61K31/275; A61K31/34; A61K31/4015; A61K31/404; A61K31/416; A61K31/4164; A61K31/4184; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/4439; A61K31/445; A61K31/47; A61K31/5375; C07C271/22; C07D207/27; C07D209/08; C07D211/14; C07D213/40; C07D213/75; C07D215/14; C07D231/56; C07D233/61; C07D233/64; C07D235/16; C07D239/42; C07D249/08; C07D257/04; C07D295/12; C07D307/52; C07D487/04; C07K5/06
Attorney, Agent or Firm:
Toshio Yano (3 outside)
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