Title:
【発明の名称】新規な抗-不整脈化合物
Document Type and Number:
Japanese Patent JP2001525388
Kind Code:
A
Abstract:
The present invention relates to novel, antiarrhythmically active phenoxyalkylamine derivatives possessing a double point of attack. More particularly, the present invention relates to new phenoxyalkylamine derivatives of the formula (1)whereinR1 and R2, independently from each other, mean hydrogen, halogen or C1-4 alkyl group;R3, R4 and R5, independently from each other, stand for hydrogen or C1-4 alkyl group;R6 represents hydrogen, C1-4 alkyl or benzyl group;R7 means nitro group or amino group optionally monosubstituted by C1-4 alkyl, benzoyl, C1-4 alkylcarbonyl, C1-4 alkylsulfonyl, C1-4 alkylcarbamoyl or C1-4 alkylthiocarbamoyl group;both n and m are 0 or 1,with the proviso that R2 is different from hydrogen, when R1 is hydrogen,as well as stereoisomers or mixtures of stereoisomers thereof, acid addition salts thereof and hydrates, prodrugs and metabolites of all these compounds.
Inventors:
Pup, Dura
Barlo, Andras
Martin, Peter
Barga, Ildico
Retage, Tibadard
Dolga, Alice
Shimei, Antal
Moravishku, Imre
Berzeny, Pal
Barrocco, Daniela
Signarella, Giorgio
Patfalshi, Malta
Barlo, Andras
Martin, Peter
Barga, Ildico
Retage, Tibadard
Dolga, Alice
Shimei, Antal
Moravishku, Imre
Berzeny, Pal
Barrocco, Daniela
Signarella, Giorgio
Patfalshi, Malta
Application Number:
JP2000524252A
Publication Date:
December 11, 2001
Filing Date:
December 10, 1998
Export Citation:
Assignee:
Zyoji Selcuta To Intet Car Fte
Saint-Georgie Albert Orbos Tudomani Edjetem
Saint-Georgie Albert Orbos Tudomani Edjetem
International Classes:
A61K31/131; A61K31/135; A61K31/165; A61K31/167; A61K31/17; A61K31/18; C07C217/14; C07C217/18; C07C233/36; C07C233/43; C07C233/78; C07C233/80; A61P9/06; C07C275/40; C07C311/08; C07C335/20; (IPC1-7): C07C217/18; A61K31/131; A61K31/135; A61K31/167; A61K31/17; A61K31/18; A61P9/06; C07C233/43; C07C233/80; C07C275/40; C07C311/08; C07C335/20
Attorney, Agent or Firm:
Shoichi Takezawa (2 outside)