Title:
【発明の名称】新規なα―グルコシダーゼ抑制剤
Document Type and Number:
Japanese Patent JP3032266
Kind Code:
B2
Abstract:
This invention relates to novel N-glycosyl derivatives of 1,4-dideoxy-1,4-imino-D-arabinitol, (Formula I) to the chemical processes for their preparation, to their alpha -glucosidase inhibiting properties, and to their end-use application in the treatment of diabetes, obesity and those diseases associated with retroviruses, particularly the HIV virus reported to be the causative of the acquired immune deficiency syndrome (AIDS). wherein n is zero, one or two, and R is a glycosyl or etherified or acylated glycosyl radical containing from 1 to 3 hexose or pentose units, said etherified or acylated glycosyl radical bearing the ether or acyl radical at the hydroxyl moiety located on the anomeric carbon atom.
Inventors:
Gene Bernard Dusep
Charles Dungin
Charles Dungin
Application Number:
JP26966790A
Publication Date:
April 10, 2000
Filing Date:
October 09, 1990
Export Citation:
Assignee:
Merrell Dow Farmers-Tikals Incorporated
International Classes:
A61K31/70; A61K31/7028; A61K31/7042; A61K31/7052; A61K31/7056; A61P3/04; A61P3/08; C12N9/99; C07H15/26; C07H19/044; (IPC1-7): C07H15/26; C07H19/044
Attorney, Agent or Firm:
Katsuro Sasai