Title:
【発明の名称】海洋放線菌に由来する新規のインドロカルバゾールアルカロイド
Document Type and Number:
Japanese Patent JP2003503412
Kind Code:
A
Abstract:
The invention provides compounds of formula (1) wherein R<1 >is a hydrogen atom, an alkyl group having 1 to 6 carbon atoms or an alkoxy group having 1 to 6 carbon atoms; and R<2 >is a hydrogen atom, an alkyl group having 1 to 6 carbon atoms or an alkoxy group having 1 to 6 carbon atoms; and pharmaceutically acceptable salts thereof. The invention also relates to a process for obtaining the compounds, compositions containing them and their therapeutic use. The compounds display excellent activity against mammalian cancer cell lines.
Inventors:
Dolores Garcia Gravaros
Julia Perez
Librada Maria Canedo
Francisco Romero
Fornando Espriego
Julia Perez
Librada Maria Canedo
Francisco Romero
Fornando Espriego
Application Number:
JP2001507035A
Publication Date:
January 28, 2003
Filing Date:
June 28, 2000
Export Citation:
Assignee:
Institut Biomar Sociedad Anonima
International Classes:
C12P17/18; A61K31/7052; A61K35/74; A61P35/00; C07D498/22; C07H19/04; C12R1/01; (IPC1-7): C07H19/04; A61K31/7052; A61K35/74; A61P35/00; C12P17/18
Domestic Patent References:
| JPH05247055A | 1993-09-24 | |||
| JPH05247055A | 1993-09-24 |
Foreign References:
| WO1994004541A2 | 1994-03-03 | |||
| US5093330A | 1992-03-03 | |||
| WO1994004541A2 | 1994-03-03 | |||
| US5093330A | 1992-03-03 |
Other References:
JPN6010047121, Ｉｎｔ． Ｊ． Ｃａｎｃｅｒ, 19890515, Ｖｏｌ．４３， Ｎｏ．５, ｐｐ．８５１−８５６
Attorney, Agent or Firm:
Masatake Shiga (7 outside)