Title:
【発明の名称】新規なオキサ又はアザステロイド誘導体
Document Type and Number:
Japanese Patent JP3293623
Kind Code:
B2
Abstract:
A compound represented by general formula (I), which has an aromatase inhibitory activity and is useful for preventing and treating diseases caused by hyperestrogenosis, such as mastocarcinoma, metrocarcinoma and prostatomegaly. In formula (I) A represents C=O, CH2, C=CH2 or C=CH-lower alkyl; B represents O, NH or N-lower alkyl; X is nil, or represents C=O or CH2; n is 2 or 3 when X is nil, or 1 or 2 when X represents C=O or CH2; and the broken line between the 1-position and the 2-position in the steroidal skeleton means an optional presence of a double bond therebetween.
Inventors:
Naoyuki Koizumi
Yoshihiro Takekawa
Shigeki Iwashita
Tomoko Kawachi
Matsui Lighting
Seijiro Homma
Hiroo Takahashi
Mamoru Saegusa
Koichi Minato
Takeo Shibata
Kouki Numazawa
Yoshihiro Takekawa
Shigeki Iwashita
Tomoko Kawachi
Matsui Lighting
Seijiro Homma
Hiroo Takahashi
Mamoru Saegusa
Koichi Minato
Takeo Shibata
Kouki Numazawa
Application Number:
JP50698592A
Publication Date:
June 17, 2002
Filing Date:
March 26, 1992
Export Citation:
Assignee:
Teikoku Organ Pharmaceutical Co., Ltd.
International Classes:
C07J73/00; (IPC1-7): C07J73/00; A61K31/58; A61P5/32
Other References:
Ｊ．Ｍｅｄ．Ｃｈｅｍ．，（１９８９），３２（３），ｐ．６５１−８
Attorney, Agent or Firm:
Heiyoshi Odashima (2 outside)