Title:
【発明の名称】P型フィムブリエを有する細菌の表面への付着の阻害に有効な植物プロアントシアニジン抽出物
Document Type and Number:
Japanese Patent JP2001515860
Kind Code:
A
Abstract:
The present invention is directed to isolation and identification of plant proanthocyanidin extracts and particular proanthocyanidin compounds for prevention and treatment of urinary tract infections caused by P-type Escherichia coli. These extracts can be obtained from any proanthocyanidin-containing plants, including plants of the families Ericaceae, Rosaceae, Pinaceae, Vitaceae and the like. Preferably the extracts are from cranberry plants (especially, Vaccinium macrocarpon) and other plants, particularly fruit and berry plants from the Vaccinium spp. The extracts and compounds are also provided as pharmaceutical compositions, food additives and food compositions, especially beverages, ground meat preparations and cranberry-containing food products. The invention also relates to methods of reducing pathogenicity of P-type E. coli in the digestive tracts of cattle and reducing P-type E. coli contamination in ground meat as well as methods of detecting P-type bacteria.
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Inventors:
Howell amy bee
Forsa Nicoli
Forsa Nicoli
Application Number:
JP2000510438A
Publication Date:
September 25, 2001
Filing Date:
September 02, 1998
Export Citation:
Assignee:
Rutgers The State University of New Jersey
International Classes:
A23B4/00; A23L1/30; A23L2/02; A23L2/38; A23L2/52; A23L13/00; A23L21/10; A61K31/35; A61K31/352; A61K31/353; A61K36/00; A61K36/18; A61K36/45; A61K36/73; A61K36/87; A61P1/12; A61P13/10; A61P13/12; A61P31/04; C07D311/62; C07D493/08; (IPC1-7): C07D311/62; A23B4/00; A23L1/06; A23L1/31; A23L2/52; A23L2/38; A61K31/353; A61K35/78; A61P1/12; A61P13/10; A61P13/12; A61P31/04
Attorney, Agent or Firm:
Nobuyuki Matsubara (2 others)