Title:
局所用ビタミンＤ口腔サプリメント組成物
Document Type and Number:
Japanese Patent JP6420766
Kind Code:
B2
Abstract:
Topical, vitamin D, oral supplement compositions useful in treating oral inflammation comprising vitamin D in an aqueous-free emulsion containing a trans-oral mucosal absorption facilitator, where said emulsion forms a mucoadhesive coating in the presence of saliva; wherein saliva dissolution of the mucoadhesive gel releases vitamin D and the trans-oral mucosal, absorption facilitator; effecting: vitamin D passive diffusion; regulating in vivo availability and immune response of vitamin D; and maintaining adequate levels of circulating vitamin D while minimizing the risk of hypercalcemia.
Inventors:
McHale William A
Brown daisy
Brown daisy
Application Number:
JP2015536896A
Publication Date:
November 07, 2018
Filing Date:
October 10, 2013
Export Citation:
Assignee:
Premier Dental Products Company
International Classes:
A61K31/592; A61K9/06; A61K9/107; A61K31/593; A61K47/06; A61K47/10; A61K47/18; A61K47/30; A61K47/34; A61K47/36; A61P1/02
Domestic Patent References:
| JP11506769A | ||||
| JP2008534629A | ||||
| JP2009523782A |
Foreign References:
| WO2009153634A1 |
Other References:
MCMAHON LAURA,INFECTION AND IMMUNITY,2011年,V79 N6,P2250-2256
Attorney, Agent or Firm:
Koichi Tsujii
Sadao Kumakura
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Sadao Kumakura
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa