Title:
抗真菌外用製剤
Document Type and Number:
Japanese Patent JP2004518696
Kind Code:
A
Abstract:
An antibacterial composition for external application, particularly, a remedial formulation for external use containing fluconazole is disclosed. The formulation comprises a base material, 0.1-5.0 percent by weight of fluconazole and 1.0-40.0 percent by weight of any one compound selected from a group consisting of fatty acid, fatty alcohol, higher fatty acid ester and lower alcohol based on weight of the base material. The composition according to the present invention has various advantages of a favorable absorption into a system through the skin of a human body and delivery of active material into horny layer of the skin, a reduced skin stimulation and an excellent stability. Therefore, the composition is efficiently useable in a medical treatment application for dermatomycosis-related infectious diseases including tinea pedis, tinea corporis, tinea cruris, tinea versicolor and/or candidiasis and the like.
Inventors:
Kim, Sun-Lin
Tan, Hyun-Kwan
Kim, Jun-Sik
Li, Ho-Beom
Min, Geun-Hong
Ryo, flies-won
Tan, Hyun-Kwan
Kim, Jun-Sik
Li, Ho-Beom
Min, Geun-Hong
Ryo, flies-won
Application Number:
JP2002562343A
Publication Date:
June 24, 2004
Filing Date:
February 07, 2002
Export Citation:
Assignee:
BORYUNG PHARMACEUTICAL CO., LTD.
International Classes:
C07D249/08; A61K9/00; A61K9/06; A61K31/4196; A61K47/00; A61K47/08; A61K47/12; A61P31/10; A61K47/06; A61K47/10; A61K47/14; A61K47/26; (IPC1-7): A61K31/4196; A61K9/06; A61K47/08; A61K47/12; A61P31/10
Domestic Patent References:
| JPS5832868B2 | 1983-07-15 | |||
| JPS6456622A | 1989-03-03 | |||
| JPH0338521A | 1991-02-19 | |||
| JPH0665076A | 1994-03-08 | |||
| JPH04321626A | 1992-11-11 | |||
| JPH09208464A | 1997-08-12 | |||
| JPH09309827A | 1997-12-02 | |||
| JPS5832868A | 1983-02-25 |
Foreign References:
| US5514698A | 1996-05-07 |
Other References:
薬学必携2 薬剤学1 調剤・製剤, JPN4007009738, 15 April 1995 (1995-04-15), JP, pages 99 - 100, ISSN: 0000871137
最近の皮膚外用剤, JPN4007009983, 10 July 1991 (1991-07-10), pages 195 - 198, ISSN: 0000839497
新・ドラッグデリバリーシステム, JPN4007009984, 31 January 2000 (2000-01-31), pages 39 - 41, ISSN: 0000839498
最近の皮膚外用剤, JPN6007014180, 10 July 1991 (1991-07-10), pages 195 - 198, ISSN: 0000946407
新・ドラッグデリバリーシステム, JPN6007014179, 31 January 2000 (2000-01-31), pages 39 - 41, ISSN: 0000946408
薬学必須２ 薬剤学Ｉ 調剤・製剤, JPN6007014181, 15 April 1995 (1995-04-15), pages 99 - 100, ISSN: 0000946409
最近の皮膚化学, JPN6009060507, 10 July 1991 (1991-07-10), pages 195 - 198, ISSN: 0001472888
最近の皮膚外用剤, JPN4007009983, 10 July 1991 (1991-07-10), pages 195 - 198, ISSN: 0000839497
新・ドラッグデリバリーシステム, JPN4007009984, 31 January 2000 (2000-01-31), pages 39 - 41, ISSN: 0000839498
最近の皮膚外用剤, JPN6007014180, 10 July 1991 (1991-07-10), pages 195 - 198, ISSN: 0000946407
新・ドラッグデリバリーシステム, JPN6007014179, 31 January 2000 (2000-01-31), pages 39 - 41, ISSN: 0000946408
薬学必須２ 薬剤学Ｉ 調剤・製剤, JPN6007014181, 15 April 1995 (1995-04-15), pages 99 - 100, ISSN: 0000946409
最近の皮膚化学, JPN6009060507, 10 July 1991 (1991-07-10), pages 195 - 198, ISSN: 0001472888
Attorney, Agent or Firm:
Masayuki Kishida
Mizuno Katsufumi
Atsushi Mizumoto
Ogawa Hidenori
Mizuno Katsufumi
Atsushi Mizumoto
Ogawa Hidenori