Title:
TOPOISOMERASE INHIBITOR
Document Type and Number:
Japanese Patent JP2001114772
Kind Code:
A
Abstract:
To obtain a new topoisomerase inhibitor inhibiting enzyme topoisomerase I related to DNA replication without causing lesion such as a cleavage in a DNA strand.
This topoisomerase inhibitor is represented by the formula (I) and obtained by culturing a microorganism belonging to the genus Thermomonospora.
Inventors:
UEDA MASARU
SUZUKI KEITARO
SUZUKI KEITARO
Application Number:
JP28916899A
Publication Date:
April 24, 2001
Filing Date:
October 12, 1999
Export Citation:
Assignee:
MERCIAN CORP
International Classes:
C12N9/99; A61K31/365; A61P35/00; A61P35/02; A61P43/00; C07D307/83; C12N1/20; C12P17/06; C12R1/01; (IPC1-7): C07D307/83; A61K31/365; A61P35/00; A61P43/00; C12N9/99; C12P17/06