Title:
GPR119レセプターのモジュレーターおよびそれに関連する障害の処置
Document Type and Number:
Japanese Patent JP2013523819
Kind Code:
A
Abstract:
The present invention relates to compounds of Formula (Ia) and pharmaceutically acceptable salts, solvates, and hydrates thereof, that are useful as a single agent or in combination with one or more additional pharmaceutical agents, such as, an inhibitor of DPP-IV, a biguanide, an SGLT2 inhibitor, or an alpha-glucosidase inhibitor, in the treatment of, for example, a disorder selected from: a GPR119-receptor-related disorder; a condition ameliorated by increasing a blood incretin level; a metabolic-related disorder; type 2 diabetes; obesity; and complications related thereto.
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Inventors:
Johns, Robert M.
Han, Sandong
Buzzard, Daniel Jay.
Lehman, Yog
Narayanan, Sangju
Yue, Dawei
Han, Sandong
Buzzard, Daniel Jay.
Lehman, Yog
Narayanan, Sangju
Yue, Dawei
Application Number:
JP2013503841A
Publication Date:
June 17, 2013
Filing Date:
April 05, 2011
Export Citation:
Assignee:
Arena Pharmaceuticals, Incorporated
International Classes:
C07D211/46; A61K31/4245; A61K31/445; A61K31/4523; A61K31/4525; A61K31/454; A61K31/4545; A61K31/497; A61K31/501; A61K31/506; A61P3/04; A61P3/10; A61P19/08; A61P19/10; A61P25/00; A61P43/00; C07D401/04; C07D401/10; C07D401/14; C07D405/12; C07D413/04; C07D413/14
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Natsuki Morishita