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Title:
腸疾患の治療
Document Type and Number:
Japanese Patent JP2008532540
Kind Code:
A
Abstract:
Methods and compositions for the treatment of intestinal disorders, such as IBD and Crohn's disease, are disclosed. Preferred compositions include siNA. Also disclosed is a method of specifically targeting siNA to treat intestinal disorders by intrarectal administration of siNA compounds.

Inventors:
Irene Gascon
Ana y Jimenez
Maria Concepcion Jimenez
Jose Pe Roman
Angela Sesto
Application Number:
JP2008501427A
Publication Date:
August 21, 2008
Filing Date:
March 14, 2006
Export Citation:
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Assignee:
Sirentis Ese A U
International Classes:
C12N15/09; A61K31/00; A61K31/7088; A61K31/7115; A61K38/00; A61P1/00; A61P1/04; A61P35/00; C12N5/10
Foreign References:
US20050272682A12005-12-08
Other References:
BOTTCHER MF ET AL., DATABASE DDBJ/EMBL/GENBANK[ONLINE], ACCESSION NO.NM_000882, SUN H ET AL., DATABASE DDBJ/EMBL/GENBANK[ONLINE], ACCESSION NO.NM_002187, N ENGL J MED., 2004年, 第351巻, 2069-2079ページ, JPN6011041526, ISSN: 0001987133
大沢利昭 他編「免疫学辞典(第2版)」, 東京化学同人, 2001年, 189-190頁, JPN6011041532, ISSN: 0001987134
J AM COLL SURG., 2005年, 第201巻, S15ページ, JPN6012017964, ISSN: 0002198324
N ENGL J MED., 2005年2月10日, 第352巻, 627-628ページ, JPN6011041528, ISSN: 0001987135
J AM COLL SURG., 2005年, 第201巻, S15ページ, JPN6012053276, ISSN: 0002352484
Attorney, Agent or Firm:
Masatake Shiga
Takashi Watanabe
Yasuhiko Murayama
Shinya Mitsuhiro



 
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