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Title:
TREATMENT OF GASTROINTESTINAL BLEEDING IN PATIENTS WITH SEVERE VON WILLEBRAND DISEASE BY ADMINISTRATION OF RECOMBINANT VWF
Document Type and Number:
Japanese Patent JP2023123738
Kind Code:
A
Abstract:
To provide a novel method for treating gastrointestinal bleeding in a subject with severe von Willebrand Disease (VWD).SOLUTION: The present invention relates to a method for treating gastrointestinal bleeding in a subject with severe von Willebrand Disease (VWD), comprising administering to the subject at least one dose of recombinant von Willebrand Factor (rVWF) ranging from about 40 IU/kg to about 100 IU/kg, wherein the first dose further comprises recombinant Factor VIII (rFVIII).SELECTED DRAWING: Figure 1

Inventors:
MIRANDA CHAPMAN
BRUCE EWENSTEIN
BETTINA PLODER
Application Number:
JP2023106554A
Publication Date:
September 05, 2023
Filing Date:
June 29, 2023
Export Citation:
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Assignee:
TAKEDA PHARMACEUTICAL
International Classes:
A61K38/37; A61K38/36; A61P1/04; A61P7/04; A61P43/00
Attorney, Agent or Firm:
Hatsushi Shimizu
Hideki Kodera
Hirotaka Yamaguchi
Shun Jinbe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Kazuya Kawamoto