Title:
グルテン不耐症および関連する状態の治療
Document Type and Number:
Japanese Patent JP6502269
Kind Code:
B2
Abstract:
Provided herein are compositions, foods comprising nepenthesin or a derivative thereof and methods of using nepenthesin or a derivative thereof for modulating gluten intolerance and related conditions, such as celiac disease. Further provided herein are pharmaceutical compositions comprising nepenthesin or a derivative thereof and methods of using nepenthesin or a derivative thereof to treat bacterial infections of the gastrointestinal tract, such as C. difficile or H. pylori. Further provided herein are compositions comprising recombinant nepenthesin I or nepenthesin II, or homologous proteins, and methods for making the same.
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Inventors:
Screamer, david
Man petr
Murazeku, high neck
Ray, Marshall
Man petr
Murazeku, high neck
Ray, Marshall
Application Number:
JP2015561852A
Publication Date:
April 17, 2019
Filing Date:
March 14, 2014
Export Citation:
Assignee:
Neptunex, LRC
International Classes:
A61K38/48; A23L29/00; A23L33/00; A61K9/16; A61P1/14
Domestic Patent References:
| JP2016501853A |
Foreign References:
| US20120225050 |
Other References:
Biochem. J., 2004, Vol.381, p.295-306
Am J Physiol Gastrointest Liver Physiol, 2006, 291, G621-G629
Am J Physiol Gastrointest Liver Physiol, 2006, 291, G621-G629
Attorney, Agent or Firm:
Ryoichi Takaoka
Nao Oda
Akiyo Iwahori
Kaoru Takahashi
Nao Oda
Akiyo Iwahori
Kaoru Takahashi