Title:
IkBキナーゼ(IKK)のインヒビターを用いる炎症性および免疫疾患の処置法
Document Type and Number:
Japanese Patent JP2004529088
Kind Code:
A
Abstract:
The present invention describes methods of preventing and treating inflammatory and immune-related diseases or disorders using inhibitors of I kappa B kinase (IKK). Also described are IKK inhibitors effective for the prevention and treatment of inflammatory and immune-related diseases or disorders, as demonstrated in vivo. Further embodiments of the present invention relate to a specific IKK inhibitors, 4(2'-aminoethyl)amino- 1,8-dimethylimidazo(1,2-a) quinoxaline and compounds of formula (I), salts thereof, and pharmaceutical compositions.
Inventors:
James Earl Burke
Steven Nadler
Kiu Yupin
Robert M Townsend
Fred Christopher Zushi
Steven Nadler
Kiu Yupin
Robert M Townsend
Fred Christopher Zushi
Application Number:
JP2002560582A
Publication Date:
September 24, 2004
Filing Date:
February 01, 2002
Export Citation:
Assignee:
BRISTOL-MYERS SQUIBB COMPANY
International Classes:
A61K31/4985; A61K31/519; A61K38/22; A61K45/00; A61P1/04; A61P9/00; A61P9/02; A61P9/10; A61P11/00; A61P11/06; A61P17/02; A61P17/04; A61P19/02; A61P25/00; A61P25/16; A61P25/28; A61P27/16; A61P29/00; A61P37/00; A61P37/06; A61P41/00; A61P43/00; C12N1/21; C07D487/04; C12N15/54; (IPC1-7): A61K45/00; A61K31/4985; A61K31/519; A61K38/22; A61P1/04; A61P9/00; A61P9/02; A61P9/10; A61P11/00; A61P11/06; A61P17/02; A61P17/04; A61P19/02; A61P25/00; A61P25/16; A61P25/28; A61P27/16; A61P29/00; A61P37/00; A61P37/06; A61P41/00; A61P43/00
Attorney, Agent or Firm:
Kyousei Tamura
Nagatoshi Shinagawa
Nagatoshi Shinagawa
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