Title:
代謝活性を上昇させるタンシノン誘導体を用いる、肥満およびメタボリックシンドロームの治療
Document Type and Number:
Japanese Patent JP2007517025
Kind Code:
A
Abstract:
The present invention relates to a composition for preventing and treating metabolic syndrome, containing tanshinone derivatives as an effective ingredient. More specifically, the present invention relates to a composition for preventing and treating metabolic syndrome, containing tanshinone derivatives that exhibit superior activity in enhancing metabolic activity, as an effective ingredient.
Inventors:
Kaku, Tefan
Park, Mungyu
Park, Mungyu
Application Number:
JP2006546850A
Publication Date:
June 28, 2007
Filing Date:
December 30, 2004
Export Citation:
Assignee:
MD Bio Alpha Company Limited
Katie and G Company Limited
Katie and G Company Limited
International Classes:
A61K36/53; A23C9/152; A23L1/30; A23L2/02; A23L2/38; A23L2/52; A61K8/63; A61K8/97; A61K9/00; A61K31/343; A61K31/58; A61K36/00; A61K36/537; A61P1/04; A61P1/16; A61P3/02; A61P3/04; A61P3/06; A61P3/10; A61P7/02; A61P7/06; A61P9/00; A61P9/04; A61P9/10; A61P9/12; A61P11/00; A61P13/12; A61P15/08; A61P15/10; A61P17/18; A61P19/02; A61P25/00; A61P25/08; A61P25/16; A61P25/28; A61P27/02; A61P27/12; A61P29/00; A61P35/00; A61P39/06; A61P43/00; A61Q19/00; A61Q19/06; C07J73/00
Domestic Patent References:
| JP2005060366A | 2005-03-10 | |||
| JPS61271210A | 1986-12-01 | |||
| JPH03123720A | 1991-05-27 | |||
| JPH02290805A | 1990-11-30 | |||
| JPH07238027A | 1995-09-12 | |||
| JP2003510286A | 2003-03-18 |
Other References:
KAMATA,K. ET AL: "Endothelium-dependent vasodilator effects of the extract from Salviae Miltiorrhizae radix. A study o", GEN PHARMACOL, vol. 24, no. 4, JPN6011010946, 1993, pages 977 - 981, XP025536808, ISSN: 0001865405, DOI: 10.1016/0306-3623(93)90176-X
KO,J.S. ET AL: "Inhibitory activity of diacylglycerol acyltransferase by tanshinones from the root of Salvia miltior", ARCH PHARM RES, vol. 25, no. 4, JPN6011010948, 2002, pages 446 - 8, XP053006907, ISSN: 0001865406, DOI: 10.1007/BF02976599
IP,S.P. ET AL: "Dihydroisotanshinone I protects against menadione-induced toxicity in a primary culture of rat hepat", PLANTA MED, vol. 68, no. 12, JPN6011010950, 2002, pages 1077 - 81, XP008112766, ISSN: 0001865407
TEZUKA,Y. ET AL: "Aldose reductase inhibitory constituents of the root of Salvia miltiorhiza Bunge", CHEM PHARM BULL (TOKYO), vol. 45, no. 8, JPN6011010952, 1997, pages 1306 - 11, XP008111762, ISSN: 0001865408
YAGI,A. ET AL: "Possible active components of tan-shen (Salvia miltiorrhiza) for protection of the myocardium agains", PLANTA MED, vol. 55, no. 1, JPN6011010954, 1989, pages 51 - 4, ISSN: 0001865409
姜兆順 他, 中国中西医結合雑誌, vol. 17, no. 1, JPN6011010960, 1997, pages 32 - 34, ISSN: 0001865410
KO,J.S. ET AL: "Inhibitory activity of diacylglycerol acyltransferase by tanshinones from the root of Salvia miltior", ARCH PHARM RES, vol. 25, no. 4, JPN6011010948, 2002, pages 446 - 8, XP053006907, ISSN: 0001865406, DOI: 10.1007/BF02976599
IP,S.P. ET AL: "Dihydroisotanshinone I protects against menadione-induced toxicity in a primary culture of rat hepat", PLANTA MED, vol. 68, no. 12, JPN6011010950, 2002, pages 1077 - 81, XP008112766, ISSN: 0001865407
TEZUKA,Y. ET AL: "Aldose reductase inhibitory constituents of the root of Salvia miltiorhiza Bunge", CHEM PHARM BULL (TOKYO), vol. 45, no. 8, JPN6011010952, 1997, pages 1306 - 11, XP008111762, ISSN: 0001865408
YAGI,A. ET AL: "Possible active components of tan-shen (Salvia miltiorrhiza) for protection of the myocardium agains", PLANTA MED, vol. 55, no. 1, JPN6011010954, 1989, pages 51 - 4, ISSN: 0001865409
姜兆順 他, 中国中西医結合雑誌, vol. 17, no. 1, JPN6011010960, 1997, pages 32 - 34, ISSN: 0001865410
Attorney, Agent or Firm:
Kenji Kawabi
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