Title:
活性なビタミンD類縁体を使用する異常増殖性疾患の治療方法
Document Type and Number:
Japanese Patent JP2004535429
Kind Code:
A
Abstract:
Methods for the utilization of hypocalcemic vitamin D analogs to inhibit the hyperproliferation of malignant or neoplastic cells without incidence of hypercalcemia.
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Inventors:
Bishop Charles W
Mathes richard bee
Mathes richard bee
Application Number:
JP2003506479A
Publication Date:
November 25, 2004
Filing Date:
June 26, 2002
Export Citation:
Assignee:
Bone Care International, Inc.
International Classes:
A01N45/00; A61K31/56; A61K31/59; A61K31/592; A61P35/00; A61P35/02; A61K45/00; A61P35/04; A61P43/00; (IPC1-7): A61K31/59; A61K31/592; A61K45/00; A61P35/00; A61P35/02; A61P43/00
Domestic Patent References:
| JPH07500848A | 1995-01-26 | |||
| JPH11506791A | 1999-06-15 | |||
| JP2002509888A | 2002-04-02 | |||
| JP2003525254A | 2003-08-26 |
Foreign References:
| WO1999049870A1 | 1999-10-07 | |||
| WO2001064251A2 | 2001-09-07 |
Other References:
JPN6009009730, ＳＨＡＮＹ，Ｓ． ｅｔ ａｌ, "Ｔｈｅ ｅｆｆｅｃｔｓ ｏｆ １ａｌｐｈａ，２４（Ｓ）−ｄｉｈｙｄｒｏｘｙｖｉｔａｍｉｎ Ｄ（２） ａｎａｌｏｇ ｏｎ ｃａｎｃｅｒ ｃｅｌｌ ｐｒｏｌｉｆｅｒａｔｉｏｎ ａｎｄ ｃｙｔｏｋｉｎｅ ｅ", Ｓｔｅｒｏｉｄｓ, 2001, Ｖｏｌ．６６， Ｎｏ．３−５, ｐ．３１９−２５
JPN6009009733, ＬＥＶＹ，Ｙ． ｅｔ ａｌ, "Ｔｈｅ ｎｏｖｅｌ ａｎａｌｏｇ １，２４（Ｓ）−ｄｉｈｙｄｒｏｘｙｖｉｔａｍｉｎ Ｄ２ ｉｓ ａｓ ｅｑｕｉｐｏｔｅｎｔ ａｓ １，２５−ｄｉｈｙｄｒｏｘｙｖｉｔａｍｉｎ Ｄ３ ｉｎ ｇｒｏｗｔｈ", Ａｎｔｉｃａｎｃｅｒ Ｒｅｓ, 1998, Ｖｏｌ．１８， Ｎｏ．３Ａ, ｐ．１７６９−７５
JPN6009009737, ＳＴＲＵＧＮＥＬＬ，Ｓ． ｅｔ ａｌ, "１ ａｌｐｈａ，２４（Ｓ）−ｄｉｈｙｄｒｏｘｙｖｉｔａｍｉｎ Ｄ２： ａ ｂｉｏｌｏｇｉｃａｌｌｙ ａｃｔｉｖｅ ｐｒｏｄｕｃｔ ｏｆ １ ａｌｐｈａ−ｈｙｄｒｏｘｙｖｉｔａｍｉｎ Ｄ２ ｍａｄｅ ｉ", Ｂｉｏｃｈｅｍ Ｊ, 1995, Ｖｏｌ．３１０ ， Ｎｏ．１, ｐ．２３３−４１
JPN6009009733, ＬＥＶＹ，Ｙ． ｅｔ ａｌ, "Ｔｈｅ ｎｏｖｅｌ ａｎａｌｏｇ １，２４（Ｓ）−ｄｉｈｙｄｒｏｘｙｖｉｔａｍｉｎ Ｄ２ ｉｓ ａｓ ｅｑｕｉｐｏｔｅｎｔ ａｓ １，２５−ｄｉｈｙｄｒｏｘｙｖｉｔａｍｉｎ Ｄ３ ｉｎ ｇｒｏｗｔｈ", Ａｎｔｉｃａｎｃｅｒ Ｒｅｓ, 1998, Ｖｏｌ．１８， Ｎｏ．３Ａ, ｐ．１７６９−７５
JPN6009009737, ＳＴＲＵＧＮＥＬＬ，Ｓ． ｅｔ ａｌ, "１ ａｌｐｈａ，２４（Ｓ）−ｄｉｈｙｄｒｏｘｙｖｉｔａｍｉｎ Ｄ２： ａ ｂｉｏｌｏｇｉｃａｌｌｙ ａｃｔｉｖｅ ｐｒｏｄｕｃｔ ｏｆ １ ａｌｐｈａ−ｈｙｄｒｏｘｙｖｉｔａｍｉｎ Ｄ２ ｍａｄｅ ｉ", Ｂｉｏｃｈｅｍ Ｊ, 1995, Ｖｏｌ．３１０ ， Ｎｏ．１, ｐ．２３３−４１
Attorney, Agent or Firm:
Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama