Title:
癌などの増殖障害の治療に有用なトリアゾール化合物
Document Type and Number:
Japanese Patent JP5523839
Kind Code:
B2
Abstract:
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.
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Inventors:
Chimanama Dine Shiyu.
Burrison Joseph A.
Ying Weiwen
Sanlijeung
Schweiser Stephan Michael
Zang Sisi
Demco Zachary
James david
Paseuroka Teresa
Burrison Joseph A.
Ying Weiwen
Sanlijeung
Schweiser Stephan Michael
Zang Sisi
Demco Zachary
James david
Paseuroka Teresa
Application Number:
JP2009549116A
Publication Date:
June 18, 2014
Filing Date:
February 08, 2008
Export Citation:
Assignee:
Shinta Pharmaceuticals Corporation
International Classes:
C07D249/08; A61K31/4196; A61K31/427; A61K31/4439; A61K31/444; A61K31/454; A61K31/496; A61K31/506; A61K31/5377; A61K31/541; A61P9/00; A61P29/00; A61P31/04; A61P31/10; A61P31/12; A61P33/00; A61P35/00; A61P37/02; A61P37/06; A61P43/00; C07D249/10; C07D249/12; C07D401/04; C07D401/10; C07D401/12; C07D401/14; C07D403/04; C07D403/12; C07D403/14; C07D405/04; C07D405/06; C07D405/12; C07D405/14; C07D417/12; C07D417/14
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Other References:
Daniela Catarzi et al.,J. Med. Chem.,1995年,Vol.38,p.2196-2201
V. V. Korshak et al.,Macromolecules,1976年,Vol.9(4),p.626-632
Brian W. Dymock et al.,J. Med. Chem.,2005年,Vol.48,p.4212-4215
C. S. Andotra et al.,Indian Journal of Heterocyclic Chemistry,1998年,Vol.8,p.139-142
S. D. LARSEN,ORGANIC LETTERS,米国,AMERICAN CHEMICAL SOCIETY,2001年 9月22日,V3 N21,P3341-3344
V. V. Korshak et al.,Macromolecules,1976年,Vol.9(4),p.626-632
Brian W. Dymock et al.,J. Med. Chem.,2005年,Vol.48,p.4212-4215
C. S. Andotra et al.,Indian Journal of Heterocyclic Chemistry,1998年,Vol.8,p.139-142
S. D. LARSEN,ORGANIC LETTERS,米国,AMERICAN CHEMICAL SOCIETY,2001年 9月22日,V3 N21,P3341-3344
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Kazuya Kawamoto