Title:
RORガンマ調節剤としての三環スルホン類
Document Type and Number:
Japanese Patent JP7182553
Kind Code:
B2
Abstract:
or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein all substituents are defined herein. Also provided are pharmaceutical compositions comprising the same. Such compounds and compositions are useful in methods for modulating RORγ activity in a cell and methods for treating a subject suffering from a disease or disorder in which the subject would therapeutically benefit from modulation of RORγ activity, for example, autoimmune and/or inflammatory disorders.
Inventors:
David Markou
Mira Board One Bertrand
T. G. Murari Dar
Michael Gee Yang
Geely Shao
Hi-Yoon Xiao
Yehen Joo
Carolyn A. Weigelt
Douglas G Butt
Mira Board One Bertrand
T. G. Murari Dar
Michael Gee Yang
Geely Shao
Hi-Yoon Xiao
Yehen Joo
Carolyn A. Weigelt
Douglas G Butt
Application Number:
JP2019545893A
Publication Date:
December 02, 2022
Filing Date:
November 08, 2017
Export Citation:
Assignee:
BRISTOL-MYERS SQUIBB COMPANY
International Classes:
C07C317/32; A61K31/13; A61K31/137; A61K31/155; A61K31/164; A61K31/17; A61K31/337; A61K31/341; A61K31/351; A61K31/381; A61K31/382; A61K31/397; A61K31/40; A61K31/415; A61K31/4152; A61K31/4162; A61K31/417; A61K31/4196; A61K31/42; A61K31/433; A61K31/438; A61K31/4409; A61K31/4412; A61K31/445; A61K31/495; A61K31/505; A61K31/5375; A61P1/04; A61P3/00; A61P11/06; A61P17/06; A61P19/00; A61P19/02; A61P25/00; A61P29/00; A61P35/00; A61P37/06; A61P37/08; C07C317/36; C07C317/40; C07C317/42; C07D205/02; C07D205/08; C07D207/09; C07D207/10; C07D207/12; C07D207/16; C07D207/277; C07D211/48; C07D211/78; C07D211/90; C07D211/96; C07D213/40; C07D213/56; C07D215/36; C07D231/06; C07D231/18; C07D233/64; C07D233/76; C07D233/90; C07D239/28; C07D241/18; C07D249/12; C07D257/04; C07D261/18; C07D263/22; C07D285/06; C07D295/15; C07D295/185; C07D305/08; C07D307/22; C07D309/10; C07D333/48; C07D335/02; C07D401/04; C07D401/12; C07D405/12; C07D471/04; C07D471/10; C07F9/09
Foreign References:
WO2007084595A2 | ||||
WO2009011851A1 | ||||
WO2009008980A2 | ||||
WO2014085211A2 | ||||
WO2015103508A1 | ||||
WO2015103509A1 | ||||
WO2015103510A1 |
Attorney, Agent or Firm:
Yamato Kento
Shinagawa
Wu Yingyan
Futami Kamahira
Masahiro Suwon
Shinagawa
Wu Yingyan
Futami Kamahira
Masahiro Suwon