Title:
トリプトリド誘導体およびその製造方法と使用
Document Type and Number:
Japanese Patent JP7096559
Kind Code:
B2
Abstract:
Disclosed are a triptolide derivative and a preparation method therefor and the use thereof. The triptolide derivative has the structure as shown in general formula I, and the definition of each substituent is as described in the description and claims. The triptolide derivative of the present invention has a better immunosuppressive activity and anti-tumor activity, and low toxicity and high safety, thus having good development and application prospects.
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Inventors:
Xiao Fei
Chiupoo
Champang
Chiupoo
Champang
Application Number:
JP2020545838A
Publication Date:
July 06, 2022
Filing Date:
April 18, 2018
Export Citation:
Assignee:
Syncate Pharmaceutical Intermediates Company Limited
Shincate Farm Tech (Shanghai) Company Limited
Shincate Farm Tech (Shanghai) Company Limited
International Classes:
C07J73/00; A61K31/58; A61P35/00; A61P35/02; A61P43/00
Domestic Patent References:
JP2007526331A |
Foreign References:
CN107663225A | ||||
WO2017136739A1 | ||||
CN106928312A |
Other References:
XU,H. et al,Design, Synthesis and Structure-Activity Relationships Studies on the D Ring of the Natural Product Triptolide,ChemMedChem,2014年,Vol.9, No.2,p.290-295
Attorney, Agent or Firm:
Nagoya International Patent Service Corporation
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