Title:
三置換アミン化合物
Document Type and Number:
Japanese Patent JP2009524579
Kind Code:
A
Abstract:
The present invention relates to a compound of the general formula (1): wherein, Y is a methylene group, and the like; A is an optionally substituted heterocyclic group, and the like; B is an optionally substituted heterocyclic group, and the like; R1 is an optionally substituted alkyl group, wherein the alkyl group further may optionally be substituted by an optionally substituted homocyclic group, and the like; and R2 is an optionally substituted amino group, and the like; or a pharmaceutically acceptable derivative thereof, which has an inhibitory activity against cholesteryl ester transfer protein (CETP), thereby being useful for prophylaxis and/or treatment of arteriosclerotic diseases, hyperlipemia or dyslipidemia, and the like.
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Inventors:
Nakamura Keisen
Norimitsu Hayashi
Takanori Higashijima
Kubota Hitoshi
Kozo Oka
Norimitsu Hayashi
Takanori Higashijima
Kubota Hitoshi
Kozo Oka
Application Number:
JP2008535216A
Publication Date:
July 02, 2009
Filing Date:
January 30, 2007
Export Citation:
Assignee:
Mitsubishi Tanabe Pharma Corporation
International Classes:
C07D215/38; A61K31/415; A61K31/4155; A61K31/47; A61K31/4709; A61K31/505; A61K31/506; A61K31/5377; A61P1/16; A61P3/04; A61P3/06; A61P3/10; A61P7/02; A61P9/00; A61P9/06; A61P9/10; A61P9/12; A61P11/00; A61P13/12; A61P15/00; A61P25/28; A61P33/12; A61P35/00; A61P39/06; A61P43/00; C07D231/38; C07D239/42; C07D401/12; C07D401/14; C07D403/12; C07D471/04
Domestic Patent References:
| JP2003221376A | 2003-08-05 | |||
| JPH0776573A | 1995-03-20 | |||
| JP2002526475A | 2002-08-20 | |||
| JP2008520645A | 2008-06-19 | |||
| JP2008528447A | 2008-07-31 |
Foreign References:
| WO2004020393A1 | 2004-03-11 | |||
| WO2004085401A1 | 2004-10-07 |
Attorney, Agent or Firm:
Kyousei Tamura
Samejima Mutsumi
Nagatoshi Shinagawa
Yasushi Morimoto
Samejima Mutsumi
Nagatoshi Shinagawa
Yasushi Morimoto