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Title:
トリプシン含有止血織物及びその製造方法
Document Type and Number:
Japanese Patent JP6940203
Kind Code:
B2
Abstract:
The disclosure provides a hemostatic fabric containing trypsin, wherein the hemostatic fabric comprises molecular sieve/fiber composite and trypsin; molecular sieve/fiber composite comprises molecular sieves and a fiber; the molecular sieves are independently dispersed on a fiber surface of the fiber without agglomeration and directly contact the fiber surface; a surface of the molecular sieve contacted with the fiber is an inner surface, and a surface of the molecular sieve uncontacted with the fiber is an outer surface; growth-matched coupling is formed between the molecular sieves and the fiber on the inner surface of the molecular sieves; the inner surface and outer surface are composed of molecular sieve nanoparticles. In the present disclosure, trypsin is specifically combined with the molecular sieve/fiber composite, which maintains a high procoagulant activity, thereby obtaining a hemostatic fabric with excellent coagulation effect. The preparation method of the hemostatic fabric of the disclosure is simple, low in cost and convenient to use, and can be widely used for wound and surgical hemostasis.

Inventors:
Fan Yi
余 麗莎
肖 麗萍
CHEN,Hao
Small strength
Application Number:
JP2020508025A
Publication Date:
September 22, 2021
Filing Date:
January 28, 2020
Export Citation:
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Assignee:
ZHEJIANG UNIVERSITY
International Classes:
A61L15/44; A61L15/24; A61L15/26; A61L15/28; A61L15/42; A61L17/00; A61L17/06; A61L17/10
Domestic Patent References:
JP2009522019A
JP2007144154A
JP2002530157A
JP4146218A
JP2264078A
Other References:
Zeolites,1996年,Vol.16,P.31-34
Attorney, Agent or Firm:
Momoko Arima
Cosmos International Patent and Trademark Office