Title:
腫瘍の治療
Document Type and Number:
Japanese Patent JP4846799
Kind Code:
B2
Abstract:
Where it was generally thought that the smallest breakdown products of proteins had no specific biological function on their own, it now emerges that the body may utilize the normal process of proteolytic breakdown to generate important compounds such as gene-regulatory or anti-tumor compounds. Such anti-tumor compounds are useful for the treatment or prevention of tumors and can be used as part of a pharmaceutical composition. The invention provides a pharmaceutical composition for the treatment of a subject suffering from or belived to be suffering from a tumor, said pharmaceutical composition comprising: a therapeutically effective amount of anti-tumor peptide or a functional analogue or derivative thereof together with a pharmaceutically acceptable diluent, wherein the peptide is preferably selected from the group VVC, LAG, AQG, LQGV (SEQ ID NO:1), QVVC (SEQ ID NO:5), MTRV (SEQ ID NO:6), AQGV (SEQ ID NO:2), LAGV (SEQ ID NO:3), LQAV (SEQ ID NO:7), PGCP (SEQ ID NO:8), VGQL (SEQ ID NO:9), RVLQ (SEQ ID NO: 10), EMFQ (SEQ ID NO:1), AVAL (SEQ ID NO:12), FVLS (SEQ ID NO:13), NMWD (SEQ ID NO:14), LCFL (SEQ ID NO:15), FSYA (SEQ ID NO:16), FWVD (SEQ ID NO:17), AFTV(SEQ ID NO:18), LGTL (SEQ ID NO:19), QLLG (SEQ ID NO:20), YAIT (SEQ ID NO:21), APSL (SEQ ID NO:22), ITTL (SEQ ID NO:23), QALG (SEQ ID NO:24), GVLC (SEQ ID NO:25), NLIN (SEQ ID NO:26), SPIE (SEQ ID NO:27), LNTI (SEQ ID NO:28), LHNL (SEQ ID NO:29), CPVQ (SEQ ID NO:30), EVVR (SEQ ID NO:31), MTEV (SEQ ID NO:32), EALE (SEQ ID NO:33), TLAVE (SEQ ID NO:38), VEGNL (SEQ ID NO:39), LNEAL (SEQ ID NO:40), VLPALP (SEQ ID NO:4), MGGTWA (SEQ ID NO:41), LTCDDP (SEQ ID NO:42), VLPALPQ (SEQ ID NO:43), VCNYRDV (SEQ ID NO:44), CPRGVNP (SEQ ID NO:45), QPLAPLVG (SEQ ID NO:46) or DINGFLPAL (SEQ ID NO:47).
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Inventors:
Kan, Nisar Ahmet
Bennell, Roberto
Wensfurt, Helt
Bennell, Roberto
Wensfurt, Helt
Application Number:
JP2008519194A
Publication Date:
December 28, 2011
Filing Date:
July 03, 2006
Export Citation:
Assignee:
Biotempt B.Fee.
International Classes:
A61K38/00; A61K38/08; A61P35/00; A61P35/04; C07K5/00; C07K5/08; C07K5/10; C07K7/00
Domestic Patent References:
| JP2003516931A | 2003-05-20 |
Foreign References:
| WO2003029292A2 | 2003-04-10 | |||
| EP1300418A1 | 2003-04-09 | |||
| US20030119720A1 | 2003-06-26 | |||
| WO2005011723A1 | 2005-02-10 |
Attorney, Agent or Firm:
Keiichiro Saikyo
Takeshi Sugiyama
Takeshi Sugiyama