Title:
調整可能な電気浸透流ポリマーコーティングキャピラリー
Document Type and Number:
Japanese Patent JP7209693
Kind Code:
B2
Abstract:
A surface-confined aqueous reversible addition-fragmentation chain transfer (SCARAFT) polymerization method was developed to coat capillaries for use in capillary zone electrophoresis (CZE). This coating produced an electroosmotic an order of magnitude lower than that of commercial linear polyacrylamide (LPA)-coated capillaries. Coated capillaries were evaluated for bottom-up proteomic analysis using CZE. The very low electroosmotic mobility results in a 200 min separation and improved single-shot analysis. Various types of coatings were prepared by simply changing the functional vinyl monomers in the polymerization mixture.
Inventors:
Dovich, Norman
Chang, Chen Bin
Chang, Chen Bin
Application Number:
JP2020507486A
Publication Date:
January 20, 2023
Filing Date:
April 18, 2018
Export Citation:
Assignee:
UNIVERSITY OF NOTRE DAME DU LAC
International Classes:
B01D57/02; C08F2/00; C08F2/38; C08F2/44; C08F20/10; C08F292/00
Domestic Patent References:
| JP2013136748A |
Foreign References:
| KR1020160107902A | ||||
| US20100137548 |
Other References:
Poly(diallyldimethylammonium chloride) as a Cationic Coating for Capillary Electrophoresis,Journal of Chromatographic Science,Vol.36,1997年,p.126-130
Attorney, Agent or Firm:
Patent Attorney Corporation Asamura Patent Office